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Intravitreal aflibercept for retinal angiomatous proliferation (RAP)
In this prospective study the authors present the visual and anatomical outcome of patients with RAP lesions who were treated with intravitreal aflibercept. The study cohort of 46 patients reached study completion at week 96. They were all Caucasians, with...
VIBIM Study: One-year results of treatment of DME with aflibercept using TnE
The VIBIM study (the treat-and-extend regimen (TER) using intravitreal aflibercept in diabetic macular edema (DME) study) was designed to evaluate the efficacy of the TER using aflibercept in the management of DME for a period of two years. The authors...
Current practice and patient selection for ISBCS in the UK
This study investigated patient and operative characteristics for immediate sequential bilateral cataract surgery (ISBCS) and delayed bilateral cataract surgery (DSCS). The annual NHS spend on cataract surgery is £500 million, a figure expected to rise by 50% in the next...
Retinal vascular occlusion from gentamicin injection post-vitrectomy
The authors present two case reports for the rare, but serious, complication of retinal vascular occlusion as a presumed result of subconjunctival injection following 25-gauge vitrectomy. Risk factors for the complication include: cardiovascular disease, retrobulbar anaesthesia, high intraocular pressure (IOP)...
Risk stratification to reduce intraoperative cataract surgical complications
The authors prospectively collected data on 1135 consecutive patients undergoing cataract surgery. They were risk stratified according to categories – A (no additional risk factors, 0 points), B (vitrectomy, corneal scarring, small pupil less than 3mm, shallow anterior chamber less...
Elevated risk of mood disorders after recurrent retinal detachment
This study was aimed to investigate the risk of mood disorders in patients who experienced retinal detachment (RD) by using the National Health Insurance Research Database in Taiwan. A total of 4129 participants diagnosed with RD and 16,516 non-RD individuals...
Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy
In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...
Clinical presentation, management, and outcomes in posterior segment open globe injuries
This is a retrospective, non-comparative, interventional case study of patients presenting with scleral and corneoscleral wounds covering a five-year period. It reports the clinical presentation, management, and factors affecting the outcomes of posterior segment open globe injuries (OGI) in 2360...
Comparison of visual field indices between normal adults and children
The authors present a prospective observational study which aimed to compare visual field indices with retinal nerve fibre layer (RNFL) thickness using optical coherence tomography (OCT) in normal adults and children. Children aged 6–18 years were recruited from a single...
