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Ethnic disparities in diagnostic sequencing yield

The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....

Diary from my elective: a Parisian experience

The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...

Recovery outcomes for ocular cranial nerve palsies

The aim of this study was to report the different causes and recovery patterns for patients with acquired and isolated ocular cranial nerve palsies in a prospective observation study of 80 consecutive patients in a single centre. There were 40...

Artificial intelligence and the 2024 Esme’s Umbrella Medical Student Essay Prize

Esme’s Umbrella is a charity for people with Charles Bonnet syndrome (CBS), helping raise awareness of the condition as well as offering support and advice. All clinical specialties may encounter CBS, so Esme’s Umbrella inaugurated a medical student essay prize...

Predictors of IOP reduction after SLT

The aim of this study was to identify predictors of intraocular pressure reduction following selective laser trabeculoplasty (SLT) in patients with primary open-angle glaucoma, who are already taking maximally tolerated IOP-lowering medication and need further IOP reduction. In this prospective...

Diabetic retinopathy and body fat distribution and adipokine secretion in type 2 diabetics

The major risk factors for diabetic retinopathy (DR) in patients with diabetes are poor glycaemic or blood pressure control, duration of diabetes and nephropathy related to the severity of DR. Several studies suggest that DR is associated with visceral fat...

Incidence of ocular myasthenia gravis and risk factors for conversion to generalised disease

This population based retrospective cohort study evaluates the incidence of ocular myasthenia gravis (OMG) as well as risk factors for transformation to generalised myasthenia gravis (GMG). Sixty-five patients (40 male and 25 female) with newly diagnosed with myasthenia gravis (MG)...

College leads call for standardised electronic health records

The Royal College of Ophthalmologists is leading an urgent joint call for the national standardisation of electronic health records (EHRs) in eyecare, which they believe is essential to improve services, outcomes and patient experience. Organisations representing professionals in primary, secondary,...

Eyelid nodule outcomes

Idiopathic facial aseptic granuloma (IFAG) is a recently defined paediatric dermatology disorder. This study presents the clinical outcomes of children with IFAG nodules on their eyelids with or without facial nodules and aim to compare the outcomes with those presenting...

Topical cyclosporine A 0.05% for recurrent anterior uveitis

This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...

Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

Assessment and management of dry eye disease

This paper is an update on the assessment and management of dry eye disease (DED). According to the second International Dry Eye Workshop 2017, “Dry eye is a multifactorial disease of the ocular surface characterised by a loss of homoeostasis...