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Embryology in clinical practice
The fascinating world of embryology is both beautiful and practical. It is a home video of our evolutionary history through the ages from the single cell through to the life aquatic, the development of gut, limbs and brain, and most...Corneal dystrophies simplified
Based on biomicroscopic and histopathologic features, corneal dystrophies can be broadly classified into epithelial, Bowman’s layer / anterior stromal, stromal, and endothelial dystrophies. Corneal dystrophies are a group of inherited, bilateral, gradually progressing, non- inflammatory conditions caused by accumulation of...
Comparison of the efficacy of anti-VEGFs agents in nvAMD
This retrospective multicentric study conducted in Israel and Canada, compared the efficacy of bevacizumab, aflibercept 2mg and ranibizumab as first-line treatments for neovascular age-related macular degeneration (nvAMD). Included were treatment-naïve nvAMD eyes receiving ≥12 months of treat-and-extend (T&E) anti-VEGF therapy...Rainspotting. Choose your future. Choose Pete’s Hidden Curriculum Part 2.
See Pete's Hidden Curriculum Part 1 here Interviewer: “Mr Murphy, what attracts you to the leisure industry?”Spud: “In a word: pleasure. It’s like pleasure in other people’s leisure.”Interviewer: “Do you see yourself as having any weaknesses?”Spud: Shakes head, then: “Oh,...Research into headlight glare commissioned by government
The government has commissioned much needed research into the causes of night-time headlight glare, after campaigning involving the College of Optometrists among others. The College spearheaded the lobbying on behalf of the optical sector, in collaboration with colleagues from the...The paradox of green: When environmental solutions lead to unintended harm
The global drive toward environmental sustainability is increasingly hampered not by outright denial, but by well-meaning solutions that conceal perverse incentives and unintended ecological consequences. Many popular ‘green’ measures, adopted by simplifying complex environmental challenges into easy substitutions or offsets,...Two cases of acute syphilitic posterior placoid chorioretinitis
Syphilis has re-emerged as a significant public health concern, with the World Health Organization (WHO) estimating that 8 million adults aged 15–49 acquired syphilis in 2022. Untreated syphilis can have severe consequences, including cardiovascular, neurological and ocular complications. Ocular manifestations...
BT outcome for CP and ET
The authors evaluate the clinical outcome of botulinum toxin (BT) injection in the correction of esotropia in 44 patients with cerebral palsy (CP). BT was injected under general anaesthesia without EMG guidance. Of the children, 47.7% were male and mean...
γδ T cell depletion does not affect fungal keratitis
Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...
ROP anti-VEGF treatment review
The purpose of this review was to consider data relating to risks and benefits of the use of anti-VEGF treatment for retinopathy of prematurity (ROP) over the past five years of 2015-2020. Ocular benefits include treatment of aggressive posterior ROP,...
