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Meibomian gland alteration in patients with primary chronic dacryocystitis: An in vivo confocal microscopy study

Chronic dacryocystitis affects tear film functionality and can predispose to ocular surface disease, however the specific effect of chronic dacryocystitis on meibomian gland function has not been studied. This group therefore performed in vivo confocal microscopy in 28 patients’ eyes...

Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases

This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...

Choroidal changes in multisystem inflammatory syndrome in children

This study aimed to evaluate the vascular structure of the choroid in multisystem inflammatory syndrome in children (MIS-C). This was a prospective study of 38 eyes of 19 patients and 60 eyes of 30 healthy controls. None had ocular pathology....

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

Diary from my elective: a Parisian experience

The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...

Baerveldt Glaucoma Implant (BGI)

The authors describe surgical outcomes using the BGI and compared the different techniques used. The main differences described in the implantation technique include the use of a prolene stent in the tube, or fixation of the tube to the sclera....

Outcomes for IRS implantation for keratoconus

The authors report visual and topographic outcomes of intracorneal ring segment (ICRS) implantation alone or in combination with corneal cross linking (CXL) and long-term results in halting keratoconus in paediatric patients. This study was a retrospective design including 19 patients...

Improving cataract efficiency: insights and learnings from expert practitioners

An evening surgical meeting sponsored by Théa Pharmaceuticals Ltd brought together leading experts to share insights and experience on practice strategies to enhance the efficiency of cataract surgery. Streamlining patient flow to optimise capacity and efficiency Qasim Mansoor, Consultant Ophthalmic...

The bionic eye – behind the headlines

Multiple visual prosthetic projects and other vision regeneration initiatives being tested in preclinical and clinical development worldwide illustrate continuing progress and opportunities in addressing profound blindness from hereditary retinal diseases and other causes (Table 1). Three implantable bionic vision systems...

My top five: Emerging alternatives to manage and treat nAMD

Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...

My Top Five: Emerging alternatives to manage and treat nAMD

Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...

How to diagnose and treat Acanthamoeba keratitis

Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...