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My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Understanding vasoproliferative retinal tumours

Syed Irtiza Ali Shah explores this rare and unusual condition through a fascinating case presentation. Vasoproliferative tumours of the retina (VPTR) are a vascular mass with an associated exudative retinopathy alongside the presence of minimally dilated feeder vessels. This is...

Intravitreal dexamethasone implant for recurrent CMO secondary to IGS

In this prospective study the authors present the data obtained on the efficacy and safety of the dexamethasone implant (0.7 mg) in the treatment of recurrent cystoid macular oedema (PCME) due to Irvine–Gass syndrome in patients with uncomplicated pseudophakia (off-label...

RPE atrophy onset in treated nAMD

In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...

Rebound phenomenon after IVT triamcinolone acetonide for macular oedema

In this retrospective study, the authors report the rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular oedema secondary to diabetic retinopathy (DR) and central (CRVO) or branch retinal vein occlusion (BRVO). The incidence of a rebound phenomenon was...

Improved quality of life in children with allergic conjunctivitis and their parents with anti-allergic therapy

This prospective intervention study investigated the change in quality of life in child-parent pairs with allergic conjunctivitis (AC) on anti-allergic therapy. From September 2020 to May 2021, AC child-parent pairs and healthy child-parent pairs were recruited in Guangzhou, China. Children...

Results of vitrectomy in epiretinal membranes secondary to retinal vein occlusions

This retrospective, observational multicentre study investigated the anatomic and functional results of vitrectomy associated with the peeling of secondary epiretinal membranes (ERM) in patients with retinal vein occlusion (RVO) and determined the prognostic factors of surgical outcomes. Data was collected...

Principles of management

Whatever section of pathology is to blame and wherever it strikes, the aim of treatment is always the same. Find the cause if you can. Establish the effects of the cause. Halt the pathological process if you can. Reverse its...

Third nerve palsy

Case scenarios A 71-year-old female presented to a nearby eye emergency unit with two days history of partial ptosis in her left eye with diplopia. She saw her GP earlier that day and he asked her to go to the...

The medical student syndrome

It is often said that “a little learning is a dangerous thing,” but being super savvy can’t put us at the brink of harm, can it? Each year as thousands of students commence their medical degrees, they begin a journey...

Simulated ocular surgery – strabismus surgery

See also Simulated ocular surgery and Simulated ocular surgery: pars plane vitrectomy and scleral buckling surgery Strabismus surgery requires a range of skills, distinct to those required for intraocular surgery. Even if a trainee does not plan to become a...