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3063 results found

Risk of CNV related to angioid streaks in PXE

This retrospective cross-sectional study investigated 301 patients with pseudoxanthoma elasticum (PXE) for prevalence of choroidal neovascularisation (CNV) and macular atrophy. Some patients were excluded due to missing or poor-quality imaging or the fact that they didn’t have angioid streaks, leaving...

Why is there subretinal fluid at the macula?

This is a review article looking at the differential diagnosis of subretinal fluid in the macula that could be diagnosed as central serous chorioretinopathy (CSCR). The authors have categorised them into 12 groups: neovascular diseases, vitelliform lesions, inflammatory diseases, ocular...

Prevalence and incidence of uveitis

Uveitis encompasses a group of diseases characterised by the inflammation of fovea uvea which are potentially vision threatening. However, the frequency of this condition is unclear. This systematic review and meta-analysis aimed to provide estimates of the frequency of uveitis...

How a paediatric population presented with diplopia

The authors present the results of a retrospective records review of 244 children presenting with diplopia over a three-year period. The majority of cases presented to paediatric ophthalmology clinic; other routes of presentation included eye casualty, neuro-ophthalmology or another eye...

Risk factors for visual impairment in facial nerve palsy

Facial nerve palsy (FNP) is known to be associated with corneal exposure due to the nature of the condition, but how many of those will go on to develop severe visual impairment (SVI)? This study investigates the risk factors associated...

Hydrogel expanders in the management of congenital anophthalmia

This is a retrospective case series of 11 anophthalmic orbits in eight children. Anophthalmia can result micro-orbitism, congenital fornix atresia, constricted socket, phimotic lids and reduced palpebral aperture. Expanders play an important role in improving the orbital volume and forniceal...

Ocular findings in children with myasthenia

This is a retrospective audit of paediatric myasthenic patients presenting to Great Ormond Street (GOSH) between January 2016 and January 2020. During this period there were 49 children, including 27 with juvenile myasthenia (JMG) and the rest as congenital myasthenia...

Children’s visual acuity test without professional supervision

With increasing outpatient demand there has been an innovative shift to involve patients managing their own condition. This article compares visual testing carried out by an orthoptist with usual clinical methods, an orthoptist using the iSIGHT Test Pro and a...

Association of strabismus with functional impairment in children in the USA

In this study the authors aimed to (1) determine if strabismus is associated with clinically significant functional impairment, (2) identify specific domains of impairment and (3) examine predictors of impairment among children aged 5-17 years. Data were extracted and analysed...

Comprehensive review of inherited retinal diseases

The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...

Infantile nystagmus syndrome and use of genetic testing

This review aimed to assess the clinical utility of genetic testing for individuals with infantile nystagmus syndrome. The authors define infantile nystagmus syndrome as having an onset before six months of age, binocular and conjugate. The literature search was conducted...

Barriers to diagnosis and management of VKC

The authors investigate the lived experience of vernal keratoconjunctivitis (VKC) diagnosis and treatment in US patients, reported by their carers and eyecare clinicians, and to identify barriers to the timely diagnosis and management of this condition. The study included seven...