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Characteristics and incidence of sixth nerve palsy in children with intracranial hypertension
The authors report the incidence and characteristics of sixth cranial nerve palsy in paediatric patients with intracranial hypertension. A retrospective review of records was performed in central Ohio over a three year period and nine children were found to have...
Retinal changes in Leber hereditary optic neuropathy
The objective of this study was to describe the changes in the retinal ganglion cell complex (GCC) relative to the retinal nerve fibre layer (RNFL) over time, in patients with Leber’s hereditary optic neuropathy (LHON). For this study, 21 patients...
Using OCT to screen and monitor Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...
Wide variation in the volume of the sphenoid trigone
This is a radiological study of the volume of the sphenoid trigone in normal subjects. The authors were interested to see how much volume could be gained by removal of the trigone during an orbital decompression for thyroid eye disease....
Two case reports of late onset adbucens nerve palsy following carotid-cavernous fistula treatment
This report presents two cases of abducens palsy developing with late onset following endovascular treatment for carotid-cavernous fistula. Following this common and effective treatment for carotid-cavernous fistula, an immediate cranial nerve palsy is a common finding. It usually resolves spontaneously....
Prostaglandin associated periorbitopathy
Prostaglandins are known to cause periorbital adverse effects. The aim of this retrospective case series was to compare the frequency of prostaglandin associated periorbitopathy (PAP) between bimatoprost, latanoprost and travoprost users. Five PAP findings were evaluated: upper lid ptosis, deepening...
Rituximab as an immunosuppression treatment for thyroid eye disease
Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...
Selection of visual field test for detection of pituitary disease
This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with...
Age-related macular degeneration in elderly persons in Germany
The authors present the findings of a cross-sectional study in 11 seniors’ community centres. Eleven community centres were screened with a total of 281 participants. A third of participants with gradable images were in normal retinal health (32%).The most common...
How accurate is the supplement content in both generic and branded ophthalmology supplements?
This prospective cross-section study compared the concentrations of Vitamin C, Vitamin E, Zinc, and Copper in five dietary supplements including both national and regional brands used for macular degeneration in the United States. They performed a comparative analysis using gas...
Idiopathic orbital pseudotumor as first sign of systemic inflammatory disease
The authors describe four children in whom idiopathic orbital pseudotumor (IOP) was the initial solitary finding with systemic inflammatory disease developing later. Four children were seen over a five-year period. Mean age was 9.75 years (2-14). Three were white and...
