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Intravitreal aflibercept for diabetic macular oedema

The VISTA and VIVID randomised phase 3 trial were designed to compare the efficacy and safety of intravitreal aflibercept injections versus laser photocoagulation for diabetic macular oedema (DMO). A total of 872 patients with centrally involving DMO were recruited, and...

Comparison of changes in ECD and CCT between CPS and FLACS

This is an intraindividual randomised clinical trial of 134 eyes from 67 patients, one eye was treated with femtosecond laser-assisted cataract surgery (FLACS) (including pretreatment of main incision, side port, capsulotomy and lens fragmentation) and the fellow eye received conventional...

SLT versus medication for OAG

This paper appraised existing randomised clinical trials (RCTs), which compared selective laser tabeculoplasty (SLT) with medical therapy for open-angle glaucoma (OAG), and performed a systematic review and meta-analysis. A total of 1229 patients in eight trials were included from PubMed,...

Visual and refractive outcomes and complications in FLACS versus CPS cataract surgery

This is a randomised, controlled study of 110 paired eyes from 55 patients that were randomised into either femtosecond laser-assisted cataract surgery (FLACS) or conventional phacoemulsification cataract surgery (CPS) groups. Visual, refractive outcomes, intraocular pressure (IOP) and complications were compared...

FA findings in treatment-naive premature infants

This retrospective study examined fluorescein angiography (FA) images of 162 eyes of 81 treatment-naive infants with retinal vascular immaturity and persistent avascular retina (PAR) despite exceeding postmenstrual age of 60 weeks. Disc diameter (DD), optic disc-to-fovea distance (FD), the length...

Preterm birth and refractive error in an Indian infant population

This study was undertaken to identify and compare the changes in refractive outcome in infants with and without retinopathy of prematurity (ROP), to inform incidence of refractive error. This was a prospective study of 300 consecutive premature infants with birth...

Patients prefer vision from lasik than from smile in a contralateral-eye trial

This prospective, randomised, single surgeon, contralateral-eye clinical trial compared the results in myopic patients undergoing wavefront-guided femtosecond laser in situ keratomileusis (LASIK) in one eye and small-incision lenticule extraction (SMILE) in the fellow eye. The patient-reported outcomes with laser in...

Laser speckle contrast imaging (LSCI) enables perfusion monitoring of the anterior segment during strabismus surgery: a study on the horizontal rectus muscles

Forty-four eyes with horizontal strabismus surgery involving medial and / or lateral rectus muscle detachment were recruited. The perfusion in the adjacent paralimbal and iris tissue was monitored with LSCI technique, by using a PeriCam PSI NR System. An infrared...

Risk for systemic hypertension in ROP with IVB or laser therapy

The purpose of this study was to investigate whether there is an association between intravenous bevacizumab (IVB) and hypertension among infants with severe retinopathy of prematurity (ROP) and comparing those treated with IVB to those treated with laser, or infants...

FSAK versus toric IOL implantation for correcting astigmatism in cataract patients

Nine studies of 590 patients were retrieved from the Ovid-Medline, EMBASE, Cochrane register of controlled trials and Scopus which compared femtosecond laser-assisted astigmatic keratotomy (FSAK) and toric IOL for astigmatism correction in cataract patients. The trial sequential analysis was used...