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The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...

Features, treatment and prevention of conjunctival inclusion cysts

Conjunctival inclusion cyst is a rare complication of strabismus surgery and generally develops at the point of muscle reattachment, caused by implantation of conjunctival epithelium. The authors aimed to determine the rate of its development after strabismus surgery and consider...

Large vs. small posterior capsulotomy size and visual angle opacification rates

The purpose of this study was to assess the relationship between posterior capsulotomy size and significant visual angle opacification (VAO) in congenital and developmental cataract. This was a retrospective case control of children aged under seven years of age over...

CRATER 2025

The Conference on Recent Advances in Translational Eye Research 2025

Headaches in ophthalmology (part 1)

Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...

Four Pillars: Leadership for clinical practice settings

This series explores the four pillars of advanced clinical practice and here, Regina Tavengwa explores the pillar of leadership and management. I have been in my current role as a matron for eight years, with a background of practicing as...

Getting started in ophthalmology: Advice for new doctors

Starting your first rotation in ophthalmology is exciting and a little daunting. As the start date approaches, the nerves may start to creep in. What’s expected of me? How much ophthalmology am I supposed to know? How will the on-calls...

What's trending Oct/Nov 2020

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #oldEnglish #herbalremedies Researchers from the University of Warwick, investigating natural remedies to treat bacterial infections, have discovered a potential new treatment....

Glaucoma: 30 years on

Back in 1993, the late and great Barry Cullen FRCS (Cavan born, Dublin trained), the first editor of Eye News, asked me to write an article about the current treatment of chronic open angle glaucoma (COAG). At the time I...

How do you solve the problem of trachoma in Ethiopia?

Background Trachoma is one of the oldest diseases known to humankind and the leading infectious cause of blindness worldwide. Spread by the bacterium chlamydia trachomatis, it is transmitted through contact with the eyes, eyelids and nose of those infected. The...

Use of orthoK for myopia treatment

This article provides an updated literature review on the orthkeratology effect on myopia progression considering outcome measures, potential effect modifiers, mechanisms and current prescription concerns. The discussion centres on the extent of slowed myopia progression, mechanisms, safety concerns and comparisons...

Orbital cellulitis in Scotland: current incidents, aetiology, management and outcomes

This is a one year prospective study using the Scottish ophthalmic surveillance unit reporting system amongst Scottish ophthalmologists. Only patients residing within Scotland with a new diagnosis of orbital cellulitis between November 2011 and October 2012 were including in this...