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New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

Inflammatory macular holes

The authors present a case of closure of a full thickness macular hole in a patient with Behçet’s disease, without surgery. The 23-year-old male they describe presented with a history of recurrent oral aphthous ulcers and a genital ulcer. Ocular...

Retinoblastoma risk factors for recurrence

This study evaluates risk factors for local tumour recurrence of main solid tumour, subretinal seed, vitreous seed and new tumour formation in eyes with retinoblastoma (RB) management with primary chemotherapy over 20 years of follow-up. The study included 960 eyes...

Ocular motility disturbances after glaucoma drainage device

This is a cross-sectional study of children (<17-years-old) with a glaucoma drainage device (GDD) (Ahmed vs Baerveldt) implanted consecutively by a single surgeon from the Toronto group, between September 2006 and May 2018 and who had an ocular motility examination...