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722 results found

Effect of observation of intermittent exotropia on health-related quality of life of children and parents

The authors present the analysis of the Intermittent Exotropia Questionnaire (IXTQ) completed by the observation arm of a previously reported randomised controlled trial comparing part-time patching to observation. Children aged >5 years completed the Child IXTQ, and all parents completed...

RCT of VR training versus occlusion for amblyopia

The purpose of this study was to compare the visual outcomes of occlusion with game playing through a virtual reality (VR) system in children with unilateral amblyopia. The study was undertaken at the Negah Eye Hospital in Iran. This was...

Pilot trial of virtual reality to treat amblyopia beyond the age of seven years

A pilot double-blind randomised controlled trial is presented. Patients were required to be between seven and 38 years of age, have a diagnosis of anisometropic and / or strabismus unilateral amblyopia, visual acuity in the amblyopic eye between 0.3-1.0 LogMAR...

Patients prefer vision from lasik than from smile in a contralateral-eye trial

This prospective, randomised, single surgeon, contralateral-eye clinical trial compared the results in myopic patients undergoing wavefront-guided femtosecond laser in situ keratomileusis (LASIK) in one eye and small-incision lenticule extraction (SMILE) in the fellow eye. The patient-reported outcomes with laser in...

RCT of unilateral vs bilateral surgery for lateral incomitance in exotropia

The purpose of this study was to evaluate and compare the surgical outcomes in the management of lateral incomitance with regard to ocular alignment and change in lateral incomitance in cases of bilateral vs. unilateral strabismus surgery. This was a...

Randomised controlled trial for large-angle exotropia surgery

The purpose of this study was to investigate single eye, single setting surgical options to correct 80–90PD of exotropia with two options of muscle transplant and suture hang-back recession. There was retention of anatomical limits of 6mm resection for medial...

Infliximab in treatment of PVR

In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...

Three-year results of 0.01% and 0.1% loading dose atropine treatment including washout in Danish children with myopia: a placebo-controlled, randomised clinical trial

This was a placebo-controlled, double-blind, randomised clinical trial of 97 children to examine the safety and efficacy of low-dose atropine (0.1% and 0.01% loading dose) after 2-year treatment and 1-year washout in 6–12-year-old Danish children with myopia. Ninety-one children were...

Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

Addressing diabetes-related complications in Tanzania and Eswatini: A comprehensive approach to eye and foot screening

Diabetes is rising globally, particularly in low- to middle-income countries (LMICs), where healthcare systems are under resourced [1,2]. Among its complications, diabetic retinopathy (DR) and diabetic foot disease are preventable yet frequently overlooked [3-6]. These problems often develop together due...

From Moorfields to Mombasa: The tale of two ophthalmology electives

Ophthalmology fascinates me because the field uniquely combines microsurgical precision with immediate, life-changing outcomes, spanning nine distinct subspecialties that seamlessly integrate medicine, surgery and cutting-edge technology. Put simply, few single organs can match the breadth and depth of pathology the...

Emerging developments in dry eye

An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...