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Apr/May 2015 Quiz

1 April 2015 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 60-year-old man presented to the ophthalmologists with painful blurred left vision. Examination revealed a white vascular mass, occupying 60% of the anterior chamber space, arising from the iris. After conservative therapy, no useful vision remained. The eye was...
Orbit journal front cover image.

Immunotherapy for orbital SCC

3 April 2026 | | EYE - Orbit
In the UK, cemiplimab is recommended for treating metastatic or locally advanced cutaneous squamous cell carcinoma (SCC) in adults when curative surgery or curative radiotherapy is not suitable. Pembrolizumab is recommended as an option for untreated metastatic or unresectable recurrent...

Identifying life-threatening uveal melanoma: A directed application of general-purpose AI

2 April 2025 | | EYE - Imaging, EYE - Oncology
Uveal melanoma (UM) is a rare but aggressive eye cancer, affecting approximately six people per million annually [1]. Uveal melanoma arises in three locations: the choroid, ciliary body, and iris. As the most common primary intraocular malignancy in adults, UM...

Effect of long-term scleral contact lenses on corneal topography, tear film and impression cytology in keratoconus

1 December 2021 | | EYE - Cornea, EYE - General
This study of 16 keratoconus patients aimed to investigate the impact of long-term scleral contact lens (ScCL) wear on corneal curvature, corneal thickness, tear film function and ocular surface in patients with keratoconus. Corneal topography, tear osmolarity test, Schirmer 1...
Journal of Pediatric Ophthalmology & Strabismus image.

Analysis of needle site after intravitreal injection for retinoblastoma

1 April 2017 | | EYE - Paediatrics, EYE - Strabismus
This study analysed the needle washings from retinoblastoma (RB) eyes receiving intravitreal Melphalon to consider risk of tumour externalisation from the procedure – 280 injections to 63 eyes in 61 patients were evaluated. Unilateral RB was present in 24 patients...
Journal of Pediatric Ophthalmology & Strabismus cover image.

Melphalon treatment of retinoblastoma

1 October 2014 | | EYE - Paediatrics, EYE - Strabismus
The purpose of this study was to report the authors’ experience with superselective ophthalmic artery infusion of Melphalon (SOAIM) for the treatment of five cases of unilateral sporadic retinoblastoma involving the macula. Standard therapy included a cycle of three infusions...
Orbit journal cover

Therapeutic options for advanced cutaneous basal (BCC) and squamous cell carcinomas (SCC)

9 August 2023 | | EYE - Oculoplastic, EYE - Orbit
This article discusses the use of topical and systemic therapy in the management of advanced periocular tumours. It focuses on those that have gained United States Food and Drug Administration approval; namely imiquimod, vismodegib, sonidegib, pembrolizumab and cemiplimab. Imiquimod is...
Ocular Oncology and Pathology journal cover image.

Tumour deposits following choroidal melanoma treatment

7 April 2021 | | EYE - Vitreo-Retinal
The authors present the unique case of retinoinvasive melanoma following treatment of choroidal melanoma with brachytherapy. Uveal melanoma, the commonest intraocular malignancy in adults, presents as a pigmented mass in the choroid, ciliary body, or iris. A 79-year-old Caucasian male...
Journal of Cataract and Refractive Surgery cover image.

Comparing tensile strengths of two scleral fixated intraocular lenses: CT-Lucia and MA60

1 June 2022 | | EYE - Cataract, EYE - Refractive
The authors designed a benchtop model to measure the tensile strengths and resistance to breakage of the haptics and haptic-optic junctions of the CT Lucia 602 (Carl Zeiss, California) and AcrySof MA60 (Alcon Laboratories, Texas) IOLs. For the haptic breakage...

Caring for adults with an ocular tumour

1 December 2015 | | EYE - Vitreo-Retinal
Detection If you screen for an intraocular tumour, dilate the pupil. If the patient is driving, use phenylephrine only. If the patient declines, document this in the casenotes. Don’t forget to look for sentinel vessels, which would indicate a ciliary...

My Top Five: Innovations in the diagnosis of ocular tumours

4 February 2025 | | EYE - Oncology, EYE - Orbit, EYE - Pathology
Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

1 February 2017 | | EYE - Oncology
Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...