You searched for "dystrophy"

289 results found

DSEK – five year results

This UK based study examined long-term descemet stripping endothelial keratoplasty (DSEK) results, looking at graft survival and endothelial cell losses. Data on 210 grafts were included in analysis. Most frequent indication for DSEK was Fuch’s endothelial dystrophy (81.4%) and 46.3%...

Penetrating keratoplasties in infants

This retrospective review looked at endothelial cell counts (ECC) following penetrating keratoplasties (PKP) performed in infants within the first year of their life. One hundred eyes of 71 patients had their first PKP during the study period (1998-2013). In 30%...

Ocular electrophysiology

A 34-year-old woman, who is a CEO in a multinational firm, has been losing vision over the last 12 months. She has seen her opticians, who initially tried different glasses but could not improve things. Clinical examination is unremarkable. How...

Feb/Mar 2018 Quiz

History A 48-year-old farmer with gradual worsening vision in her only eye was referred by her optician. She had recently moved to the UK and required an interpreter during consultation. She seemed to have had vision problems since childhood. Although...

Visual snow syndrome: a review

Visual snow syndrome (VSS) is a neurological condition characterised by visual phenomena described as dots moving across the visual field. Other visual symptoms can take the form of palinopsia, entopic phenomena, photophobia and nyctalopia. Tinnitus and migraine can be commonly...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

New study uncovers key mechanism behind a common genetic cause of age-related visual loss

A groundbreaking study has revealed important insights into the mechanisms behind Fuchs Endothelial Corneal Dystrophy (FECD), a common cause of age-related visual loss, providing hope for future therapeutic developments, and finding implications for other neurological diseases. FECD is a common,...

Cataract surgery in small adult eyes

This is a retrospective audit of a five year study period, between the periods of January 2006 to December 2010, where a surgical log book search was performed. The inclusion criteria of this study were intraocular lenses (IOL) power greater...

Fellow eye comparison of DMEK and PKP

This retrospective analysis of 11 patients who underwent penetrating keratoplasty (PKP) in their first eye followed by descemet membrane endothelial keratoplasty (DMEK) in their second eye studied visual and refractive outcomes. Intra and postoperative complications were compared and a subjective...

Alternative diagnosis in cases of poor response to amblyopia therapy

The aim of this study was to assess the prevalence of coexistent ocular pathology and identify / describe the factors that contribute to undiagnosed alternate diagnosis and / or co-existent pathology at initial presentation in patients referred as potentially amblyopic....

The Worshipful Company of Spectacle Makers awards two Master’s Medals for early career research

The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of two Master’s Medals for 2025. Fabian Yii from Edinburgh was awarded the Master’s Medal for his paper, 'Fundus Refraction Offset as a Personalized Biomarker for 12-Year Risk...

Northern Ophthalmology Trainers Society (NOTS): Cornea Update course

NOTS is delighted to present another excellent course covering high-yield topics of most important Corneal pathology. A full day of didactic Corneal and Refractive surgery update course directed at all grades of Optometrists, Ophthalmology trainees and Consultants. The course will...