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Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...

Lacrimal drainage system malignancies

This retrospective case series looks at the rare cases of lacrimal drainage system malignancies. The authors have identified 14 patients in 24 years, at a tertiary referral centre in the Indian subcontinent. Many previous publications have found squamous cell carcinoma...

Management of restrictive diplopia after ptergium surgery

This single centre retrospective case series included 15 patients with restrictive diplopia after ptergium excision. The mean time from surgery to diplopia was six months and all patients had a moderate limitation of abduction in the operated eye causing an...

Oxford Handbook of Ophthalmology (Fourth Edition)

No matter what speciality you do there will always be a couple of core textbooks that everyone seems to recommend. When it comes to ophthalmology one of the most commonly cited ones is the Oxford Handbook of Ophthalmology. Having used...

Non-organic visual loss

Patients can present to eye departments with various signs and symptoms (mostly symptoms) with no obvious organic cause. These patients can be labelled with any of a wide range of diagnoses such as functional visual loss, functional overlay, psychosomatic reaction...

Who will benefit from cataract surgery?

The need for cataract surgery is expected to rise dramatically in the future due to the increasing proportion of elderly citizens and increasing demands for optimum visual function. The aim of this study was to provide an evidence-based recommendation for...

Foveal displacement after macular hole surgery

Previous studies show that internal limiting membrane (ILM) peeling during macular hole surgery is associated with retinal shrinkage (microtubule depolymerization of the axons of the inner retina) and nasal shift of the fovea. A temporal inverted ILM flap technique was...

The results of the last survey Feb 2020

I appreciate that I keep on reiterating it, but again we see so much practice variance. Who is right and who is wrong? Is there a right or wrong approach? And does it matter? I think it probably does matter....

Cluster of cyclic esotropia cases

This study reports a series of five patients with cyclic esotropia presenting within a period of 19 months in 2015-16 in one institute. Brain MRI scans were abnormal in two patients (twins) with abnormal white matter signal in the frontal...

Cavernous sinus syndrome

Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...

Evaluation of Optive® in ocular discomfort after anti-VEGF intravitreal injection

In this study the authors prospectively evaluated the efficacy of Optive® eye drops after in full, then abbreviation - intravitreal injection (IVT). Patients naïve to IVT were included in the study. No artificial tear treatment was prescribed after the first...

VDT use and dry eye disease in children

There has been an increase in the amount of work performed using video display terminals. This study compared school children with and without dry eye disease and evaluated the risk factors of dry eye disease and evaluated the risk factors...