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The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Scheimpflug imaging in paediatric glaucoma
The authors undertook this study to report the corneal tomographic characteristics of eyes that had surgery for controlled primary congenital glaucoma (PCG) compared to a control group. The study included 44 eyes of 27 children (18 males) having surgery for...
Effective contrast ratio as a measure of binocular visual perception
The authors used a binocular phase combination paradigm to quantitatively evaluate and compare the binocular visual perception of normal individuals and patients with different types of strabismus to understand the binocular visual perception of patients with strabismus and evaluate whether...Refractive surprise after cataract surgery caused by posterior capsular striae
Cataract removal with intraocular lens (IOL) implantation is one of the most frequently performed surgeries in current clinical practice [1,2]. New microsurgical techniques and refined IOL power calculations allow excellent refractive outcomes. Refractive surprise following cataract surgery is uncommon [1-3]...
Microsporidia-induced stromal keratitis: a new cause of presumed immune stromal (interstitial) keratitis
This is a non-comparative retrospective observational case series from India from 1 October 2020 to 31 January 2021. The inclusion criteria were: (1) presence of nummular / coin shaped lesions with at least one >2mm in size and / presence...
Multicentre PCO rates in different brands of monofocal intraocular lenses
This was a longitudinal, retrospective cohort study featuring 47,754 (three years) and 20,763 (five years) eyes with age-related (≥65 year) cataract surgeries between 2010-2013 across seven UK ophthalmology clinics. The three- and five-year incidence of posterior capsular opacification (PCO) and...Moorfields: Endonasal DCR Hands-on Simulation Course
Moorfields: Endonasal Dacryocystorhinostomy (DCR) Hands-on Simulation Course
Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)
The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...
Does mitomycin C improve success rates in DCR surgery?
The authors present a meta-analysis of the use of mitomycin C (MMC) as an adjunct in dacrocystorhinostomy (DCR) surgery. Fifteen randomised control trials were included. There was a degree of heterogeneity in the surgical technique used, however, the MMC is...
Latanoprost in the treatment of congenital glaucoma
The aim of this study was to investigate the glaucoma control of latanoprost therapy in primary congenital glaucoma (PCG) and assess the factors affecting long-term outcome. Eighty-one eyes of 44 patients with PCG and 42 eyes of 29 patients with...
Factors influencing the outcome of GT and TBT in PCG
This is a retrospective study between 2013 to 2016 of 452 eyes of patients </=12 years with primary congenital glaucoma (PCG), who underwent either goniotomy (GT) (median age: six months, 120 eyes) or trabeculotomy (TBT) (median age: 5.2 months, 332...
