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Systemic fungal infections and corneal transplants
This prospective study looked at corneal donors with positive medical history of systemic fungal infection (oral thrush or respiratory, urine, wound, sputum, bronchial, tracheal, or throat culture positive for fungus), to establish if the risk of post-keratoplasty fungal eye infections...
Maintenance therapy for CMV endotheliitis
Cytomegalovirus (CMV) has been associated with corneal endotheliitis, leading to endothelial cell loss and corneal decompensation. CMV corneal endotheliitis recurrence can affect between 5-60% of eyes after cessation of anti-CMV therapy. Each recurrence of endotheliitis has a detrimental effect on...
γδ T cell depletion does not affect fungal keratitis
Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...
Corneal stroma modelling under hypoxic conditions
The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...
Erythropoietin in healing corneal epithelial defects in rabbits
Corneal epithelial defects heal slowly in patients with diabetes, limbal stem cell deficiency and severe chemical burns. Erythropoietin is a glycoprotein hormone that promotes red blood cell proliferation and inhibits apoptosis of erythroid progenitors as well as nonhematopoietic cells. In...
Factors influencing the outcome of GT and TBT in PCG
This is a retrospective study between 2013 to 2016 of 452 eyes of patients </=12 years with primary congenital glaucoma (PCG), who underwent either goniotomy (GT) (median age: six months, 120 eyes) or trabeculotomy (TBT) (median age: 5.2 months, 332...
