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ABCA1 mediates lipid efflux in the retina
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...
Reproducible OCT RNFL map in unilateral glaucoma
The aim of the study was to compare the reproducibility of the optical coherence tomography retinal nerve fibre layer (OCT RNFL) thickness map between glaucomatous and fellow normal eyes of unilateral glaucoma patients. The authors carried out a prospective case...
Long scleral tunnel technique to prevent tube exposure of Ahmed glaucoma valve
This retrospective study was done to evaluate the efficacy of long scleral tunnel technique and compare it with pericardium patch graft in preventing tube exposure of Ahmed glaucoma valve. Seventy-eight eyes of 73 patients were included. In group 1 patients,...
Occult spread of squamous cell carcinoma into the orbit
The authors describe two cases that may represent perineural spread of cutaneous squamous cell carcinoma (SCC) into the orbit. Both cases had cutaneous squamous cell carcinomas in the region of the lateral orbital wall (innervated by the zygomatico-temporal nerve) which...
Meibomian gland dropout in patients with dry eyes
In this prospective study 264 patients with symptoms of dry eye were examined with a non-contact meibography system to assess the morphological changes in their meibomian glands. These patients were not previously diagnosed with meibomian gland dysfunction and patients with...
Akimba mice, a model of human diabetic retinopathy
Diabetic retinopathy (DR) is a major complication of diabetes and a growing problem as the systemic disease becomes more prevalent. DR develops insidiously from an asymptomatic form through to vascular damage that leads to oedema and breakdown of the blood-retinal...
Visual fields and OCT in hydroxychloroquine retinopathy
It has been recommended that patients on hydroxychloroquine be monitored regularly for retinopathy. However, there has not been an agreement as to the best screening test for hydroxychloroquine toxicity, which may include visual fields (VF), fundus autofluorescence, spectral domain optical...
MicroRNA inhibits corneal neovascularisation
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
A case of post-viral ocular microflutter
A number of eye movements disrupt visual fixation, one such movement being saccadic intrusions which are described as small involuntary saccadic movements. Among saccadic intrusions without intersaccadic intervals, ocular flutter and opsoclonus are prominent. When the saccadic amplitude is very...
A relationship between central serous retinopathy and obstructive sleep apnoea
This prospective study aimed to evaluate a relationship between central serous retinopathy (CSR) and obstructive sleep apnoea (OSA). Twenty-three subjects (six female and 17 male) were diagnosed with CSR and overnight polysonography was performed to record desaturation and apnoeic episodes....
Diabetic retinopathy and body fat distribution and adipokine secretion in type 2 diabetics
The major risk factors for diabetic retinopathy (DR) in patients with diabetes are poor glycaemic or blood pressure control, duration of diabetes and nephropathy related to the severity of DR. Several studies suggest that DR is associated with visceral fat...
