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2605 results found

Test combination which could detect prodromal Alzheimer disease

The authors prospectively recruited a convenience sample of individuals aged over 65 and either with a diagnosis of mild cognitive impairment (MCI) due to Alzheimer disease or normal cognition. Other types of dementia and severe neurological conditions were excluded. All...

Detection of SO tendon abnormality versus atrophy

This study aimed to evaluate patterns of binocular misalignment in primary gaze, lateral and vertical gaze, and head tilt in patients showing head-tilt dependent hypertropia associated with discontinued superior oblique (SO) tendon but without SO muscle atrophy, versus patients with...

Proof of concept for using aqueous humour to detect retinoblastoma variant

A proof of concept study is presented with the aim of assessing the feasibility of using aqueous humour surrogate marker for tumour tissue for identifying retinoblastoma RB1 variant. Three children undergoing enucleation for retinoblastoma were recruited from a single centre....

Atopic dermatitis: Risk of glaucoma progression?

This population-based retrospective cohort study from December 5, 2003 to December 3, 2018 examined 528,469 patients with glaucoma with a diagnosis of atopic dermatitis (AD) based on diagnostic claim codes from the TriNetX Research Network, which contains real-time information on...

Function vision outcomes in pseudophakic children

This study evaluated the functional vision of 196 pseudophakic children and their carers treated at a tertiary centre in Southwest Nigeria and identified association factors. Mean age was 9.8 ±3.4 years (range 2–16) with 68.9% male and 31.1% female. Median...

The use of virtual reality in paediatric ophthalmology

The purpose of this study was to investigate the utility of virtual reality (VR) in the broader field of paediatric ophthalmology with review of examination, screening, diagnosis, prevention and treatment. This review also explores the potential of eye tracking used...

AI glaucoma screening cost-effective in the Netherlands?

Population-wide screening for glaucoma has traditionally been deemed not cost-effective due to high costs and low disease prevalence. This Dutch study re-evaluates this position by introducing artificial intelligence (AI) to the screening model. The authors developed a health-economic model comparing...

Sclerochoroidal calcification masquerading as ocular malignancy

Case 1 A 68-year-old Caucasian gentleman was urgently referred to eye casualty by his optometrist after seeing an unusual incidental finding of protruding lesions from the retina, suspecting choroidal melanoma. He was asymptomatic and this was his first eye test...

Unveiling Diabetes – Historical Milestones Diabetology (Frontiers in Diabetes)

For readers who may not be familiar with the history of diabetes research, this book provides an insight into the personalities that made major contributions; the recognition and honours conferred on those individuals and their respective colleagues, and the forgotten,...

Serology testing in periocular inflammatory disease

This is a review article of serological tests in thyroid eye disease, IgG4-related disease and myasthenia gravis. The authors provide an overview of the current serology with a brief description of how they relate to the pathogenesis of each condition....

A review of chromosome 9p21 POAG susceptibility locus

Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...

Patient satisfaction after refractive lens exchange with an EDOF lens

The aim of this study was to identify independent factors associated with postoperative satisfaction after refractive lens exchange with an extended depth of focus intraocular lens (EDOF IOL). Patients who underwent a refractive lens exchange with bilateral implantation of the...