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A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model
This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...
Optimising treatment with transscleral cyclophotocoagulation
This study compares the outcomes of transscleral diode laser cyclo-photo-coagulation with the treatment parameters used. This was a retrospective chart review of a random sample of diode laser procedures using the G-probe over 10 years for uncontrolled glaucoma. The main...
Effect of change in retinal nerve fibre layer thickness on quality of life in patients with glaucoma
The authors investigated the relationship between structural changes in glaucoma (retinal nerve fibre layer (RNFL) thickness) and quality of life (as measured by the NEI VFQ-25 questionnaire) over a period of time. Two hundred and sixty eyes of 130 patients...
Steroid treatment for pseudophakic cystoid macular oedema
The authors present a retrospective comparison of 45 eyes of 41 patients treated with 2mg intravitreal triamcinolone (IVT group) and 50 eyes of 42 patients treated with 40mg sub-Tenons triamcinolone (STT group) for pseudophakic cystoid macular oedema (CMO). The visual...
OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema
This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....
Changes in corneal endothelial layer after strabismus surgery
The purpose of this study was to investigate the changes in the corneal endothelial layer by specular microscopy after surgery in patients with horizontal and oblique strabismus. Eighty-three eyes of 56 patients were evaluated prospectively. There were three subgroups: one...
Risk of fractures with glaucoma
In this systematic review and meta-analysis, 7 articles were analysed, with 570,694 subjects and a reported total of 45,957 fractures. The study protocol (CRD42024527785) was registered prospectively. PubMed, EMBASE, and Web of Science were searched from their inception to April...Strengthening eye care services in Botswana through the Botswana-Addenbrooke’s Abroad VISION 2020 LINK
The VISION 2020 LINK between Botswana and Addenbrooke’s Abroad has been running for 10 years. With support from the VISION 2020 LINKS Programme two-way exchange visits were undertaken leading to the formation of the first formal international partnership under Addenbrooke’s...Unilateral Single Wall Decompression of Thyroid Proptosis Following an Incidental Traumatic Injury
Case report A 69-year-old female with a long history of Grave’s ophthalmopathy was under routine follow-up when it was noted during a clinic visit that the amount of proptosis and lid retraction in her right eye had remarkably reduced. A...
How long to wait to refract after instilling cyclo drops for children with brown irides?
This study aimed to assess the time needed for effective cycloplegia after instillation of 1% cyclopentolate drops in children with brown irides. The study recruited 161 consecutive patients aged three to 16 years. All had refraction on arrival, then instillation...
Normative database of OCT measurements in children
This study aimed to establish a normative database of optical coherence tomography (OCT) (Cirrus SD-OCT) parameters and to investigate if gender, ethnicity and axial length affect these measures by evaluating the effects of age and spherical equivalent refraction (SER) in...
