This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...
This review examines how the extracellular matrix (ECM) is remodelled throughout uveal melanoma development, from the eye to the liver. Uveal melanoma, the most common primary intraocular malignancy in adults, carries a poor prognosis due to its propensity for hepatic...
The authors aimed to explore the strengths and weaknesses of 2 different large language model (LLM) chatbots (ChatGPT4.0 and DeepSeek-RI) in providing reliable and access information about paediatric ophthalmology. The study used 44 multiple choice questions covering topics from the...
1 February 2016
| Fiona Harris, Spyridon Chalkiadakis, Simon Taylor (Prof)
|
EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...
Case report Choroidal metastasis represents a common form of intraocular malignancies occurring in up to 10% of patients with systemic metastasis [1]. The most common primary sites of ocular metastasis are breast carcinoma in women and lung carcinoma in men,...
I’m here with Chris Gordon and Anthony Vukic from Gloucestershire Hospitals NHS Foundation Trust to find out how two professions that may appear unrelated on the surface actually have a lot in common. Some of this article might surprise you....
Using some captivating artwork, Iheukwumere Duru describes key features of pigment dispersion syndrome. Pigmentary dispersion syndrome (PDS) leads to pigmentary glaucoma (PG) in approximately 35-50% of patients with the condition [1]. PG is the leading cause of non-traumatic blindness in...
“In the midst of tragedy, we start the comedy” – Agatha Christie, The ABC Murders. Throughout a career in medicine, we are often faced with tragedy. One of the coping mechanisms is to use humour to navigate the mini everyday...
When people ask me what life in the laboratory is really like, I often pause. On one hand, it is the romantic notion of pushing back the boundaries of science with the daily rhythm of experiments, data and easily obtained...
Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...