You searched for "Neuro-ophthalmology"

2618 results found

Efficacy and safety of intravitreal aflibercept injection in wet age-related macular degeneration

This is a sub-group study of double masked review of patients randomised to different dosages and treatment frequency compared between aflibercept and ranibizumab treatment. This is to evaluate the efficacy and safety of intravitreal aflibercept (IVT-AFL) in Japanese patients with...

Effect of selenium and vitamin E supplements on the development and progression of cataracts

The Selenium and Vitamin E Cancer Prevention Trial (SELECT) investigated the influence of dietary supplements on the development of prostate cancer in a group of 35,533 middle aged and older, apparently healthy men. The SELECT Eye Endpoint (SEE) study is...

Is there an association between dry eye disease and depression and anxiety?

Dry eye disease is a widespread ocular surface condition (prevalence 5.5-33.7%) that has been previously linked to systemic diseases, such as Sjogren, rheumatoid arthritis and more recently possibly also depression, in small population-based studies. The authors’ aim was to investigate...

Cataract surgery in small adult eyes

This is a retrospective audit of a five year study period, between the periods of January 2006 to December 2010, where a surgical log book search was performed. The inclusion criteria of this study were intraocular lenses (IOL) power greater...

Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

Injection frequency and anatomic outcomes following conversion to Aflibercept in neovascular AMD patients

This is a retrospective study of patients with neovascular age-related macular degeneration (AMD) treated with intravitreal Lucentis and / or Avastin who were switched to aflibercept (Eylea). This study was carried out by the Casey Eye Institute retinal clinics, between...

Intraoperative floppy iris syndrome and prevalence of intraoperative complications

Alpha-blockers (particularly of the selective type) are known to be associated with intraoperative floppy iris (IFIS) and poor dilation, which can present in various severities during cataract surgery and need to be recognised in order to avoid intraoperative complications. Methods...

Anterior and posterior capsular opacification with the Tecnis ZCBOO and AcrySof SA60AT IOL

This a randomised, controlled, prospective and double-blind study comparing the anterior capsular opacification (ACO) and posterior capsular opacification (PCO) outcomes with two types of single-piece hydrophobic acrylic intraocular lenses (IOL), and AcrySof SA60AT – Group A, and Tecnis ZCBOO –...

Secondary iris-claw anterior chamber lens implantation in patients with aphakia without capsular support

This retrospective, non-randomised, non-comparative, interventional study including 128 eyes of 124 patients that presented with aphakia with no capsular support. All patients consecutively underwent Artisan iris-claw intraocular lense (IOL) implantation between 1997 and 2010. The inclusion criteria were: aphakic without...

Epiretinal membranes in uveitic macular oedema

Epiretinal membrane (ERM) formation in uveitic macular oedema is a fairly common structural complication of the retina. The authors describe a retrospective case series of 104 eyes of 77 patients with uveitic macular oedema from a tertiary centre. The treatment...

DISC lens slow myopia progression in Hong Kong Chinese schoolchildren

This is a prospective double-blind randomised trial between September 2007 and October 2009. It included 221 children aged 8-13 years, with myopia between -1 and -5 Dioptres ≤1.00D. There were 111 patients in the defocus incorporated soft contact DISC group...

How does cataract surgery affect eyes with wet AMD?

In this retrospective cohort study the authors’ primary objective was to assess whether cataract surgery in eyes with wet age-related macular degeneration (AMD), triggered its progression. The surgical group comprised of 40 eyes versus 42 eyes in the non-surgical control...