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Orbital Schwannomas

This is a large case series of orbital Schwannomas managed at a single centre over a 26-year period. Twenty Schwannomas are reported, all but one of which was managed surgically. The tumours were all benign, had an insidious onset and...

Microvasculature changes of mCNV after ranibizumab treatment using OCTA

In this study the authors aim to evaluate the vascular changes of myopic choroidal neovascularisation (mCNV) after ranibizumab treatment using optical coherence tomography-angiography (OCTA). The 3×3 OCTA en face images were analysed for the absence / presence of mCNV, CNV...

The willingness of patients to participate in an eye donation registry for research

This paper explores the willingness of ophthalmic patients to donate their eyes post-mortem for research purposes. A total of 300 German patients with a median age of 70 years (range 19-95) completed the standardised questionnaire; 45.3% were female and the...

What caregivers know about VKC and effect of this on compliance

The authors aimed to determine the knowledge, attitude, and practice among caregivers of children with vernal keratoconjunctivitis (VKC) to assess their level of understanding of the disease and factors that affect compliance with medical advice and compel them to use...

Cost-effectiveness of orthoptic-delivered screening versus school nurse screening

The authors describe a long-term audit of outcomes and costs associated with referrals from two established neighbouring school-entry vision screening services in the UK over one academic year with one adhering to national UK screening guidelines more closely than the...

Transient thickening of the macular retinal nerve fibre layer in acute optic neuritis

Acute optic neuritis (ON) causes axonal degeneration, which can be quantified from the blood by neurofilament protein (Nf) levels. Within about three months, atrophy of the retinal nerve fibre layer (RNFL) follows. However, it remains challenging to explain why there...

Elevated risk of mood disorders after recurrent retinal detachment

This study was aimed to investigate the risk of mood disorders in patients who experienced retinal detachment (RD) by using the National Health Insurance Research Database in Taiwan. A total of 4129 participants diagnosed with RD and 16,516 non-RD individuals...

Patterns of binocular diplopia in giant cell arteritis (GCA)

Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...

Evisceration in India: demographic and clinical trends from a large multicentre cohort study

In this multicentre cohort study, the authors investigated a total of 2071 patients who underwent evisceration with primary implant placement over a six-year period at four tertiary eyecare centres in India. Out of 1,345,480 new ophthalmic presentations during the study...

Clinical presentation, management, and outcomes in posterior segment open globe injuries

This is a retrospective, non-comparative, interventional case study of patients presenting with scleral and corneoscleral wounds covering a five-year period. It reports the clinical presentation, management, and factors affecting the outcomes of posterior segment open globe injuries (OGI) in 2360...

Balancing early and late surgical intervention for congenital nasolacrimal duct obstruction

This retrospective study investigated the incidence of anisometropia and amblyopia by age of congenital nasolacrimal duct obstruction (CNLDO) resolution. At Seattle children’s hospital, between 2007 and 2017, the outcomes of children with early versus late spontaneous resolution of CNLDO were...

OCTA in diabetic macular oedema treated with intravitreal aflibercept (DOCTA Study)

Central vision loss due to diabetic macular oedema (DME) can be attributed not only to presence of the macular oedema itself but also, in some cases, to alterations of the foveal avascular zone (FAZ). The DOCTA trial was a longitudinal,...