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2426 results found

Long-term incidence and survival trends in retinoblastoma in the USA

The authors present a retrospective observational study of 5730 patients diagnosed with retinoblastoma between 1996 and 2018. Data on demographics, age at diagnosis, treatment and survival were extracted from national registries with coverage of 99% of the population of the...

Aetiology of painful ophthalmoplegia

Painful ophthalmoplegia is a clinical syndrome presenting with periorbital / hemi-cranial pain and ipsilateral ocular motor nerve palsies and can occur with numerous different diseases. In this study, the authors aimed to determine the final definite aetiology among patients with...

Nystagmus in infants (0–1 year)

This article from a tertiary hospital in Jerusalem documents the examination and investigations of 147 infants aged 0–1 years with nystagmus. The most common pathologies were albinism (59%) and inherited retinal dystrophy (IRD) (21%). They had eight patients with vertical...

AI glaucoma screening cost-effective in the Netherlands?

Population-wide screening for glaucoma has traditionally been deemed not cost-effective due to high costs and low disease prevalence. This Dutch study re-evaluates this position by introducing artificial intelligence (AI) to the screening model. The authors developed a health-economic model comparing...

Aug/Sep 2014 Quiz 2

History A 27-year-old man presented to the emergency department with blurred vision and central scotoma in the right eye (RE) over the previous weeks. He had no relevant medical history and he was not on any current medication. However, he...

Exploiting nature’s randomised trials of eye disease

Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

Bionic eyes: deciphering the neural circuitry of vision restoration

As the boundaries between technology and biology blur, retinal prosthetics, often dubbed ‘bionic eyes’, present a ground-breaking paradigm shift in addressing blindness. This article delves into the captivating scientific intricacies of these neural interfaces, exploring their mechanisms of action, current...

In conversation with Clare Abbott (ECLO)

Rosalyn Painter spoke to Clare Abbott, a member of the Eye Clinic Liaison Officer (ECLO) team at Oxford Eye Hospital, about her day-to-day job as an ECLO, how the role can help patients, and the ongoing importance of their work....

A window to 2024 and beyond?

The connection between the eye and systemic diseases has been acknowledged for millenia. Historical records suggest that ancient civilisations had some understanding of the eye’s significance beyond its primary function in vision. For instance, in ancient Egypt, the ‘Eye of...

Beyond vision loss: Why doctors should know about Charles Bonnet Syndrome

Over 250 years have passed since Charles Bonnet’s seminal essay, in which he described the symptoms of the syndrome that now takes his name [1]. Charles Bonnet Syndrome (CBS) describes the occurrence of visual hallucinations in people with significant visual...

What's trending Jun/Jul 2022

A round-up of the eye-related hot topics that have been trending over the last few weeks. #Polishdoctor #UkraineConflict #familysight Polish doctor Professor Rejdak’s team saved a Ukrainian family’s eyesight after a bomb hit their home. Olena Selichzianowa and her 5-year-old...

‘The Way Forward’ champions clinicians as architects of patient-centred service redesign

The demographic time bomb poses the dilemma of how more healthcare can be delivered to the UK’s ageing population without commensurate growth in resources. The Way Forward Project provides a robust resource for clinical centres to better identify and implement...