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Intravitreal bevacizumab vs. ranibizumab in the treatment of macular oedema due to BRVO

This is a randomised, prospective, non-inferiority trial of 75 patients with macular oedema due to a branch retinal vein occlusion (BRVO) who received intravitreal injections of ranibizumab or bevacizumab after 1:1 block randomisation. This study is to measure the difference...

Cataract surgery in small adult eyes

This is a retrospective audit of a five year study period, between the periods of January 2006 to December 2010, where a surgical log book search was performed. The inclusion criteria of this study were intraocular lenses (IOL) power greater...

Congenital dacryocystocele in UK

The authors report the first national study of dacryocystocoeles in UK. They report an incidence of one in 18,597 live births in the UK for congenital dacryocystocele. A prospective observational study of 49 cases of congenital dacryocystocele presenting between September...

Rebamipide 2% for dry eye

Rebamipide is a quinolinone derivative that has been found to increase mucin production and the number of conjunctival goblet cells. A previous phase two study has shown rebamipide 2% to be better than placebo in improving the ocular surface and...

Aflibercept treatment in polypoidal choroidal vasculopathy

The authors present a study to evaluate the anatomical and functional efficacy of aflibercept intravitreal (IVT) as a monotherapy in polypoidal choroidal vasculopathy (PCV) in a Caucasian population treated with initial three-monthly aflibercept IVT, followed by a bimonthly regimen for...

Retinal vascular occlusion from gentamicin injection post-vitrectomy

The authors present two case reports for the rare, but serious, complication of retinal vascular occlusion as a presumed result of subconjunctival injection following 25-gauge vitrectomy. Risk factors for the complication include: cardiovascular disease, retrobulbar anaesthesia, high intraocular pressure (IOP)...

Early vitrectomy for endophthalmitis offers hope to patients

A Phase 2 feasibility study published today in the prestigious Nature Communications Medicine journal has shown that early vitrectomy surgery treatment for acute endophthalmitis can be potentially more beneficial to patients’ vision compared with the current antibiotic-first approach. This is...

Two-year GATHER2 data: anatomical gains, functional questions for avacincaptad pegol in geographic atrophy

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) remains a leading cause of irreversible central vision loss, and complement dysregulation has long been implicated in its pathogenesis. In 2023, the US FDA approved the first two GA therapies, both...

Report: UKEGS 2024

It was an incredible experience heading down to UKEGS 2024 earlier this month in Southampton. The entire Glaucoma UK team, along with the UKEGS overseeing panel Nishani Amerasinghe, Andrew Tatham, Professir Anthony King and Professor Gus Gazzard, took great care...

Uveal melanoma

Uveal melanoma is the most common primary intraocular tumour. However, they are still rare, with an incidence of 2-8 per million [1]. The presence of a choroidal naevus is a risk factor for uveal melanoma [1]. Patients with choroidal lesions...

Maximising the ocular surface prior to cataract surgery: The old and the new modalities of treatment

Cataract surgery is among the most commonly performed surgical procedures worldwide. Over time, it has evolved from a lens-extraction procedure into a refractive intervention that demands meticulous perioperative planning and precision to achieve optimal outcomes. Optimisation of the ocular surface...

The eye as a window to the brain: Non-invasive neuromonitoring

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. Neuromonitoring, for example in conditions causing raised intracranial pressure (ICP) such as...