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Autophagy in lens mitochondria loss

The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Intraocular pressure reduction after cataract surgery

Several studies have shown the efficacy of cataract surgery in lowering intraocular pressure (IOP), especially in angle closure glaucoma compared to open angle. A total of 156 eyes of 109 patients (without glaucoma or with medically controlled glaucoma) were included....

The global burden of age-related macular degeneration

Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...

Childhood blindness and visual impairment in the Narayani Zone of Nepal

Up to 50% of childhood blindness is preventable or treatable, and its control is a high priority in the VISION 2020 initiative of the International Agency for the Prevention of Blindness. In this study, the authors utilised the rapid assessment...

Topical nonsteroidal ant-inflammatory drugs (NSAIDs) in patients undergoing cataract surgery

Inflammation is a major risk factor for the development of cystoid macular oedema (CMO) after cataract surgery, leading to breakdown of the blood-retina barrier. There is a correlation between severity of CMO and level of postoperative inflammation. Laser flare meter...

Factors leading to loss to follow-up after strabismus surgery in children.

One hundred and fourteen patients were identified as lost to follow-up between 2014 and 2020, representing 16% of paediatric strabismus surgery performed during this time period. The authors specifically defined lost to follow-up as not attending follow-up appointments between three...

Occult central retinal artery occlusion

Central retinal artery occlusion (CRAO) is a sight-threatening condition resulting from occlusion of the central retinal artery and hypoperfusion of the inner retina. Early on, fundal examination may be normal. The authors present a retrospective case series of 11 patients...

Complications of limbal stay sutures

There is limited literature describing complications at the limbal suture site. The authors describe two cases with postoperative complications due to use of intraoperative limbal stay sutures. Each case had strabismus surgery at other centres but with presentation to the...

Usher syndrome patient reported outcomes

The authors present a systematic review of the literature on patient-reported outcomes in Usher syndrome; a leading cause of deaf-blindness. A total of 27 studies were included, and there was a strong bias towards studies from the US and Europe...

Ethnic variation in strabismus patterns in Down syndrome

The authors present a systematic review and meta-analysis evaluating the prevalence and aetiology of strabismus in individuals with Down syndrome, with particular focus on ethnic variation in the esotropia to exotropia ratio. Data from multiple studies across diverse populations were...