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MicroRNA mediate retinoblastoma signal transduction

1 October 2014 | | EYE - Vitreo-Retinal
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...

Understanding amniotic membrane grafts

1 June 2019 | | EYE - Cornea, EYE - General
Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...

Acute dellen formation post trauma

1 January 2016 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Corneal dellen are saucer-like thinnings, usually of the peripheral cornea [1]. Dellen formation is thought to be related to localised tear film instability [2], specifically the absence of the mucin component of the tear film. Without the mucin layer, dry...

Is patient masking leading to an increase in post-op infection after eyelid surgery?

21 October 2020 | | EYE - Oculoplastic
Due to the COVID-19 pandemic, the use of facemasks or face coverings in the clinical setting has become necessary. It is important to recognise that facemasks can be a source of infection after eye surgery and consider ways to minimise...

Third nerve palsy

1 August 2017 | EYE - Neuro-ophthalmology, EYE - General
Case scenarios A 71-year-old female presented to a nearby eye emergency unit with two days history of partial ptosis in her left eye with diplopia. She saw her GP earlier that day and he asked her to go to the...

The curse of the college museum

4 December 2024 | | EYE - General
David Greig lecture notebook. Courtesy of Dr Jacqueline Cahif, College Archivist, Royal College of Surgeons of Edinburgh. As sure as the inevitability of death and taxes, the hidden stories of past events will intermittently rise to the surface like oil...

What's trending Aug/Sep 2018

1 August 2018 | | EYE - General
A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #QueenElizabeth #cataract It is well and truly summer! Queen Elizabeth was spotted in her sunnies during recent events, not just...

60 Seconds with Mainline Instruments Ltd

23 May 2022
We spoke with Jonathan Sugden from Mainline Instruments Ltd about their plans for the future and the icare Eidon ultra-widefield imaging device.

Unravelling ocular motility

1 April 2016 | | EYE - Neuro-ophthalmology
Ocular motility can often be a slightly abstract concept during the earlier years of ophthalmology training. A large variance on what embodies normality; mythical concepts like fusion and binocular vision, examination techniques that can be fiddly, and complex neuroanatomy all...

The Worshipful Company of Spectacle Makers awards two Master’s Medals for early career research

21 October 2025 | WCSM, early career, awards, genetics, AI
The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of two Master’s Medals for 2025. Fabian Yii from Edinburgh was awarded the Master’s Medal for his paper, 'Fundus Refraction Offset as a Personalized Biomarker for 12-Year Risk...

Diagnosis and management of IV cranial nerve palsy

1 October 2017 | EYE - Neuro-ophthalmology
Aetiology: Trochlear nerve palsy can be divided into acute or congenital. Congenital trochlear nerve palsy is usually noted in childhood with development of abnormal head posture. Various pathologies can lead to acute IV nerve palsy, most commonly trauma. Other causes...