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2718 results found

Assessing everyday visual function in dry AMD – what matters to the person?

Age-related macular degeneration (AMD) is the primary cause of blindness in the developed world and is accountable for more than one half of sight impairment registrations within England and Wales [1]. AMD is prevalent in people aged 60 years and...

COVID-19 and Charles Bonnet Syndrome

As COVID-19 rips through the country, it is – of course – imperative that we stay at home to try and prevent the virus spreading through the whole community. We are all aware of the need to take special care...

Supranuclear ocular motility disorders

Figure 1: Bilateral INO Introduction Complex ocular motility disorders are a diagnostic challenge. These patients come with very complex ocular motility presentations and require a careful and detailed assessment in order to find the correct diagnosis and arrange appropriate investigations....

Effects of phacoemulsification on IOP and drug use in glaucoma

For patients with comorbid cataract and primary open-angle glaucoma (POAG), guidance is lacking as to whether cataract extraction and traditional filtering surgery should be performed as a staged or combined procedure. Achieving this guidance requires an evidence-based understanding of the...

Chronic drop use and trabeculectomy on tear osmolarity

Ocular surface disease (OSD) is common in patients chronically treated for glaucoma. This may be related to the drug itself but often to the preservatives in the medication. Much work has been done on the most common preservative, benzalkonium chloride...

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Cytokine levels in vitreous fluid in patients with pathological myopia

Pathological myopia (PM) is a leading cause of irreversible visual impairment worldwide, and efforts are dedicated to the study of its underlying mechanisms. Axial extension of the eyeball is regulated via a cascade of biochemical molecules that are initiated in...

Complaints, Litigation and Clinical Errors: A Practical Guide for Health Care Students and Professionals

This concise book provides readers with practical guidance to help them to both avoid errors and develop robust processes to protect themselves and their patients, as well as dealing appropriately with complaints and litigation, when things do go wrong. Free...

Stem cell therapy for Parkinson’s disease: researching for an 
effective cure

Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...

Early bird bookings are open for Optometry Tomorrow 2024 – now incorporating BCLA Focus

Taking place from 28-29 April 2024, at the Telford International Centre, the flagship conference of The College of Optometrists now incorporates the biennial UK conference of the British Contact Lens Association.

Risk factors for lens dislocation post cataract surgery

This retrospective cohort study in Korea assessed the risk factors for intraocular lens (IOL) dislocation. They used national data of 2,162,191 patients who had had cataract surgery between 2009 and 2016. They excluded any patient who had an IOL dislocation...

Exploiting nature’s randomised trials of eye disease

Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...