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Reduction of severe visual loss and complications following IAC for RB
This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...
Selection of visual field test for detection of pituitary disease
This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with...
Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience
Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...
The rarebit vision test for macular conditions
Rarebit testing is used to measure low degrees of neuro-visual damage and is available for free on the internet. It consists of a fixed bright light dot presented on a black background. During testing it is presented briefly at different...
Differential diagnosis of inflammatory optic neuritis
The authors present the differential diagnosis of inflammatory optic neuritis (ON) to include multiple sclerosis, infectious optic neuritis, systemic disease and neuromyelitis optica (NMO). The features of ON for the varying aetiologies are detailed including incidence and overlap. In acute...
Molecular genetics of achromatopsia
Achromatopsia is a rare autosomal recessive disorder of the cone photoreceptors. Typical characteristics of affected patients include the inability to distinguish colours, impaired visual acuity, photophobia and nystagmus. The condition is said to be more frequent in the Pingelapese population...
BT for retinal detachment strabismus
The authors report the use of botulinum toxin (BT) as a treatment option in 140 patients with strabismus relating to retinal detachment surgery. The BT dose was 2.5 units of Dysport. Mean follow-up was 27 months (3-203) with a mean...
Review of extraocular muscle biopsies and utility of biopsy in extraocular muscle enlargement
This is a retrospective case series study from Melbourne, Australia, of 93 patients with extraocular muscle (EOM) enlargement who underwent an EOM biopsy between March 1992 and January 2017. Statistical analysis was performed to compare the data between patients with...
Diclofenac versus Bromfenac after cataract surgery
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used after cataract surgery to reduce inflammation and cystoid macular oedema (CMO). Diclofenac 0.1% is used three to five times daily for 28 days and Bromfenac 0.09% twice daily for 14 days postoperatively. The...
Tear production levels and dry eye disease
Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...
Is pre-eclampsia / eclampsia a risk factor for non-infective uveitis?
This population based retrospective matched cohort study was the first of its kind to suggest an association between preeclampsia / eclampsia (PEE) and non-infective uveitis (NIU). They used the Longitudinal National Health Insurance database in Taiwan to assess 2073 post-delivery...
