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2873 results found

Melphalon treatment of retinoblastoma

The purpose of this study was to report the authors’ experience with superselective ophthalmic artery infusion of Melphalon (SOAIM) for the treatment of five cases of unilateral sporadic retinoblastoma involving the macula. Standard therapy included a cycle of three infusions...

Laser photocoagulation vs. intravitreal (IVT) aflibercept for ROP

The efficacy, recurrence rate and requirement for additional treatment were compared between laser photocoagulation and IVT of 1mg/0.025ml aflibercept in the treatment of retinopathy of prematurity (ROP). The study included 27 babies (51 eyes) who completed a follow-up period after...

Effect of long-term RGP-CL wear on keratoconus progression

This is a retrospective study between April and December 2017, of 22 rigid gas-permeable contact lens (RGP-CL) patients (31 eyes) and 15 non-CL patients (20 eyes) who fulfilled the criteria of: 1) >3 years follow-up and 2) Scheimpflug-based corneal imaging...

ROPScore for detection of any and severe ROP

ROPScore is a free tool consisting of a logistic regression equation to calculate the risk per child and calculated one time per infant at six weeks of life. It helps to predict severe retinopathy of prematurity (ROP). This study aimed...

New prognostic model for multiple sclerosis after optic neuritis presentation

The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...

Combined versus traditional photocoagulation treatment for aggressive posterior retinopathy of prematurity (APROP)

The purpose was to report the outcomes of the combined treatment of sparing laser photocoagulation and intravitreal Bevacizumab (IVB) treatment versus conventional laser photocoagulation intervention in APROP. This was a study of 18 eyes of nine infants. One was excluded...

Chorioretinal atrophy in punctate inner choroidopathy / multifocal choroiditis

This study reported the five-year outcomes of chorioretinal atrophy (CRA) progression in patients with punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) in 45 eyes of 36 patients. The mean age of the cohort of patients was 37 ±13.37 years...

Histopathology-guided management of ocular surface squamous neoplasia (OSSN) with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy

This is a retrospective interventional consecutive case series of 42 eyes of 42 patients with OSSN with histopathologically proven corneal stromal and / or scleral invasion following excision biopsy. The mean tumour basal diameter was 9.3mm and thickness of 3.1mm...

Likelihood of developing multiple sclerosis after optic neuritis diagnosis

Optic neuritis (ON) is a relatively common cause of acute optic neuropathy in young patients which often presents as the first sign of multiple sclerosis (MS). There is a lack of evidence around the factors that are associated with the...

Efficacy of augmented-dosed surgery versus botulinum toxin A injection for acute acquired concomitant esotropia

This is a retrospective study of 104 patients diagnosed with acute acquired concomitant esotropia (AACE) between 2020 and 2022. Potential factors that influence the dose-response of bilateral medial rectus recession (MRec) and the rate and risk factors for ACCE relapse...

Risk for systemic hypertension in ROP with IVB or laser therapy

The purpose of this study was to investigate whether there is an association between intravenous bevacizumab (IVB) and hypertension among infants with severe retinopathy of prematurity (ROP) and comparing those treated with IVB to those treated with laser, or infants...

Characteristics of central serous chorioretinopathy by age

The authors present a cohort study of 326 patients with simple central serous chorioretinopathy (CSC) according to the classification system laid down by Chhablani, et al. in 2020. Genotyping for two variants of the CFH gene rs800292 and rs1329428 was...