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A review of chromosome 9p21 POAG susceptibility locus
Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...
Sclerotomy suturing
This was a retrospective review of 589 consecutive cases of patients who underwent 23-gauge tranconjunctival pars plana vitrectomy. Cases were split into Type 1 vitrectomies (macular hole, ERM and simple vitreous haemorrhages) and Type 2 cases which were more complex...
Using frequency doubling technology perimetry to identify Alzheimer’s disease early
Alzheimer’s disease is widely reported to be associated with deficits in visual function. Visual disturbances include impaired stereopsis, contrast sensitivity and motion detection. Deficits specific to the magnocellular pathway (MGC) have been identified in Alzheimer’s disease. This article compares the...
Direct endoscopic probing for congenital lacrimal duct obstruction
The most common treatment for congenital lacrimal duct obstruction (CLDO) is probing, which is traditionally a blind procedure. Previous literature reports success rates between 78-92%. The authors of this retrospective non comparative case series reviewed the success rates of probing...
Macular slippage following macular hole surgery
The treatment of macular holes now involves peeling the internal limiting membrane (ILM) as well as vitrectomy and gas tamponade. It has been noted in previous studies that following an ILM peel the morphology of the macula is different. Tadayoni...
Corneal thickness in patients with diabetic peripheral neuropathy
This cross-sectional study assessed corneal thickness in association with diabetic peripheral neuropathy (DPN) severity. The study also tried to identify the layer of the cornea most affected by DPN status. Performed at the University of Michigan the study included three...
Comparison of ketorolac 0.4% and nepafenac 0.1% for the prevention of CMO after phacoemulsification
This is a prospective randomised clinical trial study including patients older than 40 years with age related cataract and normal ophthalmic examination. The patients are randomised into three different groups and the objective of the study is to compare the...
Changes in refractive error in patients with accommodative esotropia after being weaned from hyperopic correction
This is a retrospective review of medical records of 47 patients with refractive ocular accommodative esotropia who achieved emmetropisation and orthotropia without hyperopic glasses correction and were followed up for at least three years. The objective of the study is...
Evaluation of keratometry with a novel colour LED corneal topographer
The Cassini topographer (i-Optics), which analyses corneal shape based on the reconstruction of specular reflections on 679 coloured LEDs, generates keratometry and is the new machine being compared in this study with other keratometry devices. The prospective comparative study included...
Smartphone based visual acuity
Smartphone technology is becoming widely available to all age groups and settings. Apps using Snellen acuity charts are widely available and this study evaluated the equivalence of a smartphone-based visual acuity chart with a standard 6m Snellen visual acuity (6SVA)...
Four year outcomes of macular degeneration treated with ranibizumab
The authors report on a retrospective study of neovascular age-related macular degeneration (AMD) patients treated with a variable ranibizumab dosing regimen over a period of four years (from January 2007 to December 2011). A total of 600 treatment naïve eyes...
