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Upper eyelid ulceration as a presenting sign of frontal sinus mucocele

3 October 2022 | | EYE - General
Introduction A sinus mucocele is an epithelium-lined sac filled with mucus and desquamated epithelium. It forms secondary to inflammatory processes that occur in a sinus with an obstructed ostium. Predisposing conditions include previous trauma, surgery, tumours, anatomical abnormalities, and chronic...

Letter from America: Orbit and oculoplastic fellowship, University of California, San Diego

1 June 2014 | | EYE - Oculoplastic, EYE - Orbit
I was the fortunate recipient of the 2012 Keeler Scholarship, granting me the incredible opportunity to undertake a fellowship at the University of California, San Diego (UCSD) in orbital, oculoplastic and reconstructive surgery. My fellowship mentors were the renowned Professor...

Human factors in the operating room

3 June 2021 | | EYE - Cataract, EYE - Refractive, EYE - General
The importance of minimising human error in surgery is well established. This was initially sparked by lessons learned from the aviation industry in the 1970s after several fatal flight accidents [1]. This became a catalyst for a movement on training...

Pathophysiology of diabetic macular oedema: why combination therapy may be better

1 October 2015 | | EYE - Vitreo-Retinal
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

New solutions in the prevention and treatment of Acanthamoeba keratitis

5 October 2020 | | EYE - Cornea, EYE - General
The global increase in Acanthamoeba keratitis infections has emphasised the inefficiencies of current treatment and preventative methods, here researchers from the West of Scotland detail a promising new series of compounds that may stem the tide. News headlines detailing horror...

Time is vision in central retinal artery occlusion

4 August 2021 | | EYE - Vitreo-Retinal, EYE - General
Central retinal artery occlusion (CRAO) is a rare but devastating vascular episode that can have severe impact on vision. Treatment is very time-limited and needs to be initiated very quickly to salvage any vision. The majority of patients present to...

Poppers retinopathy: What is it and how do we treat it?

2 June 2025 | | EYE - Vitreo-Retinal
Poppers retinopathy is a relatively unknown phenomenon which afflicts users of poppers but should be considered as a differential in sudden-onset or sub-acute visual acuity loss – particularly in patients with a history of recreational drug use. Raising awareness of...

Progressive myelination of the retinal nerve fibre layer: Acquired or incidental?

4 August 2025 | | EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Paediatrics
*Co-first authors.Myelinated retinal nerve fibres are retinal nerve fibres encased by a myelin sheath, located anterior to the lamina cribrosa [1]. First described by Virchow in 1856, a myelinated retinal nerve fibre layer (RNFL) appears as a whitish, feathery patch...

Understanding spaceflight-associated neuro-ocular syndrome (SANS): what do we know?

2 August 2022 | | EYE - Oculoplastic, EYE - General
Introduction Formerly known as visual impairment and intracranial pressure syndrome (VIIP), space-related neuro-ocular syndrome (SANS) is defined by a collection of ophthalmic and neurological findings in astronauts after long-term spaceflight [1]. Changes in the eyeball, such as hyperopic shift, during...

Orbital cellulitis - an overview of the diagnosis and management

1 February 2022 | | EYE - Orbit, EYE - Neuro-ophthalmology, EYE - Imaging, EYE - General
Periorbital (preseptal) and orbital cellulitis are infections of the subcutaneous tissues of the eye. They are differentiated by the location of the infection. Periorbital cellulitis refers to infection of the eyelid and subcutaneous tissues anterior to the orbital septum, whereas...

Breakthroughs in the genetics of angle-closure glaucoma

1 April 2017 | | EYE - Glaucoma
Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Pigmented paravenous retinochoroidal atrophy

4 December 2024 | | EYE - Imaging, EYE - Vitreo-Retinal
Presentation A 46-year-old Caucasian female was referred to the eye clinic by her local optician following a routine sight test. She was noted to have pigmentary retinal changes in both eyes but was asymptomatic with no visual complaints. At presentation...