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The International AMD Genomics Consortium study: another success in understanding the complex genetics of AMD

Age-related macular degeneration (AMD) is a neurodegenerative complex disease of the eye and a major cause of blindness and visual impairment among the elderly worldwide. The early stages of the disease are characterised by asymptomatic pigmentary abnormalities and accumulation of...

Personalising the management of dry eye disease: TFOS DEWS III updates evidence-based recommendations

Dry eye disease (DED) is a heterogenous condition that arises from various aetiologic factors and leads to tear film instability, ocular surface damage and neurosensory changes. Symptoms of DED include ocular dryness, burning, itching, pain and visual impairment. An evidence-based...

“I can see fine. Why do I need my eyes tested?”

Are routine eye examinations really necessary? The author asks whether frequent appointments in low-risk patients with normal results are actually cost-effective. It’s recommended that most people should get their eyes tested every two years.” [1] This message is widely publicised...

The Preston Rule

The selection, specification and fitting of a spectacle frame necessitates the recording of certain measurements particular to the frame. These measurements are also essential when it is required to manufacture a handmade spectacle frame. Instruments designed to accomplish this task...

Novel changes during COVID-19 – transforming a walk-in Eye Casualty to a telephone triage service

With the current pandemic climate due to COVID-19, out of the norm approaches have been adopted in different hospitals across the UK to ensure patient safety. At our Eye Casualty (EC) department at Northampton General Hospital (NGH), we felt the...

Gemini Untwined: treating craniopagus conjoined twins

The authors discuss the successful separation of craniopagus conjoined twins at Great Ormond Street Hospital and the role of the ophthalmologist in such cases. Craniopagus conjoined twins are extraordinarily rare, occurring in only one in 2.5 million births and representing...

Dr William Mackenzie: a founding figure of modern ophthalmology

The author looks at the career of William Mackenzie and the important role he played in establishing the status of ophthalmology as a recognised medical speciality. There are certain individuals who, blessed with ability and means, are destined to leave...

Irido-corneal endothelial syndrome: an overview

Irido-corneal endothelial (ICE) syndrome is a rare group of eye related disorders that constitute three different clinical entities: Chandler syndrome (CS), essential / progressive iris atrophy and iris naevus / Cogan-Reese syndrome. ICE syndrome is sporadic in its presentation as...

Implications of missed foreign bodies under the upper eyelid

Children aren’t the best historians. As a result, clinicians sometimes rely on the accounts of parents regarding problems. Missed foreign bodies due to poor histories or incomplete examinations may result in irreversible loss of vision. This case report shines light...