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MicroRNA inhibits corneal neovascularisation

MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

A case report of cavernous sinus syndrome following dental procedure

This case report describes a patient presenting with painful diplopia as a consequence of root canal dental treatment. Following root canal treatment a non-resolving tooth pain led to a decision to extract the tooth, leading to onset of severe periorbital...

Enzymatic clearance of anterior chamber infiltrate in uveitis

Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...

How to be a better optometrist – a personal view

Our optometry editor shares her personal observations of what makes the best optometrist. Some years ago in Glasgow, I gave a presentation with this same title, ‘How to be a better optometrist’. I was the optometry programme director for NHS...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

The management of chronic uveitis

A 40-year-old company executive is referred from another unit with recurrent anterior and posterior uveitis for 12 months and the inflammatory markers are raised. Review of systems This is a case of chronic uveitis which needs a thorough workup and...

Acute management of retrobulbar haemorrhage

The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...

Displacement of submacular haemorrhage – comparative study pneumatic displacement versus subretinal cocktail injection

The authors report a multicentre retrospective interventional case series study comparing the outcome of submacular haemorrhage (SMH) using pneumatic displacement with intravitreal expansile gas versus treatment with pars plana vitrectomy (PPV) versus subretinal injection of tissue plasminogen activator (tPA), anti-vascular...

Conference Report: Uveitis-North West: Weaving a vision at the Whitworth Art Gallery

“It is necessary to mark the greater from the lesser truth: namely the larger and more liberal idea of nature from the comparatively narrow and confined; namely that which addresses itself to the imagination from that which is solely addressed...

XXII SARCS (State of the Art Refractive Cataract Surgery) Symposium 2024

by Andrew Bourne, BSc, MCOptom, DipTp(IP), Dip Glauc, Principal Optometrist, Hull & East Yorkshire Eye Hospital, UK. Once again, Milind Pande welcomed over 220 ophthalmologists and allied professionals to his annual symposium, this year held once again at the University...

The adverse effects of COVID-19 on undergraduate ophthalmology education: An opportunity to reform ophthalmology training

The steady erosion of undergraduate ophthalmology teaching, which has been acutely exacerbated by the COVID-19 crisis, has led to a lack of basic ophthalmology examining skills and knowledge amongst clinicians of other specialities. Concurrently, there has been a rise in...

EU: is it time to leave and embrace the world?

Should the United Kingdom remain a member of the European Union (EU) or leave? It’s a big decision involving some complex issues, and there’s no doubt the EU will continue to change. Ipsos MORI’s monthly EU voting intention poll published...