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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Ophthalmology clinical teaching and research fellowships: a pathway into ophthalmology specialty training

Ophthalmology is known for being one of the most competitive medical specialties in the UK, with 6.8 applicants per post in 2021. In fact, the competition ratio has drastically increased in recent years, rising from 5.73 in 2020 and 3.24...

A novel integrated practice unit (IPU) approach to periocular skin cancer management

The COVID-19 pandemic was one of the biggest challenges to face NHS workers. However, history has repeatedly shown that times of difficulty can result in the development of significant social and technological advances. We describe our own experience of this...

Investigating the link between corneal clarity and statin use

Transparency is a vital attribute of the cornea, necessary in preserving healthy vision. Maintaining this requires the collective input of the various layers of the cornea. Mostly, the layers implicated in this are the corneal stroma and endothelium [1]. Our...

Strabismus and ocular motility, demystified

I am a former orthoptist, now trained in medicine and working as a foundation doctor. In my previous work, I was frequently approached by ophthalmology trainees eager for guidance with strabismus and ocular motility. Drawing on my clinical experience, I...

In conversation with Charles Leclercq (ARxVision)

Julian Jackson (Founder and Director, VisionBridge) spoke to Charles Leclercq (CEO, ARx) about the ARxVision, a wearable device that captures the world around us through audio and artificial intelligence to empower blind and low-vision individuals. You can read the Eye...

Maximising the ocular surface prior to cataract surgery: The old and the new modalities of treatment

Cataract surgery is among the most commonly performed surgical procedures worldwide. Over time, it has evolved from a lens-extraction procedure into a refractive intervention that demands meticulous perioperative planning and precision to achieve optimal outcomes. Optimisation of the ocular surface...

Primary eye health care in low- and middle-income countries

The need for eyecare services in low- and middle-income countries Recent global estimates (2020) suggest that there is more than a three-fold difference in the prevalence of all categories of visual loss (presenting visual acuity <6/12 in the better eye)...

Survey of current undergraduate ophthalmology teaching in the United Kingdom

Is there a crisis in ophthalmic education? The British Undergraduate Ophthalmology Society surveyed medical students and junior doctors to evaluate current ophthalmology teaching across medical schools in the UK. British medicals schools are currently not obligated to include ophthalmology within...

Treatment of diabetic macular oedema

Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...

Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies

An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...

Eye Capacity: clinical need should drive ophthalmic service provision

Almost two million people in the UK suffer sight loss, a number forecast to double over coming decades. Major causes of blindness are age-related macular degeneration (AMD), glaucoma, diabetic retinopathy, cataract and uncorrected refractive error. Prevalence of these sight-threatening conditions...