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Intravitreal bevacizumab vs. triamcinolone in patients with DMO at the time of cataract surgery
This prospective, single masked randomised control trial (RCT) compared visual and anatomical outcomes when either intravitreal bevacizumab (BVB) or triamcinolone (TA) was administered at the time of cataract surgery and at subsequent review, if required, in patients with diabetic macula...
Optimising treatment with transscleral cyclophotocoagulation
This study compares the outcomes of transscleral diode laser cyclo-photo-coagulation with the treatment parameters used. This was a retrospective chart review of a random sample of diode laser procedures using the G-probe over 10 years for uncontrolled glaucoma. The main...
Ten-year experience with intracameral chemotherapy for aqueous seeding in retinoblastoma: long-term efficacy, safety and toxicity
This is a retrospective review of all consecutive patients with primary (n=4) or secondary non-iatrogenic (n=16) aqueous seeding (AS) treated by intracameral chemotherapy (ICC) in Lausanne between 2011 and 2020 with a minimum follow-up of one year. Aqueous seeding control...
Update: Non-infectious retinal vasculitis
This review article summarises the update on non-infectious retinal vasculitis (RV). It is primarily classified based on the type of retinal vessels involved and further sub-classified as occlusive or nonocclusive. Clinically it can occur as an isolated ocular entity or...Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...My Top Five: Visionary inventions in ophthalmology
When we see how technologically forward and advanced modern-day medicine is, we forget that it is also an age-old, ancient profession with a rich, intriguing history that we remain unaware of. Ophthalmology in particular has always been at the forefront...Regulatory drug evaluations and expedited review initiatives: EU and US perspectives
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...
Optical coherence tomography in patients exposed to vigabatrin
Vigabatrin is used to treat epilepsy and can lead to increased levels of gamma-aminobutyric acid (GABA) in the brain and in the retina leading to binasal visual field defects. Although not the first line of treatment for adults it is...
Strabismus and scleral buckling
The authors examine the incidence of strabismus following scleral buckle for retinal detachment surgery and the factors that influence the strabismus, its incidence, preventative measures and treatment options. This was a retrospective review of 344 patients (360 eyes) with a...
Surgical oculocardiac reflex
The authors evaluated the incidence of oculocardiac reflex (OCR) during strabismus surgery to determine its associated risk factors at a tertiary referral centre. Seventy-six patients were reviewed; 51.3% male and a mean age of 15±12 years. Strabismus surgery was bilateral...
Surgery for horizontal nystagmus
The authors report two consecutive interventional surgical series in which the authors describe their experience with the Sinskey anterior extirpation procedure (SAEP) and a newly modified myectomy without reattachment (MWR). In a review of 39 patients, 20 underwent the SAEP...
