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Biomarkers in thyroid eye disease

An ideal biomarker is sensitive, specific, easily assessable and clinically relevant. This study looked at the presence of inflammatory cytokines present in the tear film of healthy controls, thyroid patients without eye disease (non-TED) and those with thyroid eye disease...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...

Cutting-edge practice in glaucoma care: what, how and why?

More effective treatments and drug delivery modalities, implantable minimally invasive glaucoma surgical (MIGS) devices, as well as accelerating clinical research programmes, will transform the surgical and clinical management of glaucoma in the near future. There is also an ever-greater emphasis...

Dropless cataract surgery

Dropless cataract surgery (DCS) describes the complete provision of anti-inflammatory and antibiotic prophylaxis intraoperatively. This eliminates the need for postoperative eyedrops to be self-administered by the patient and thus is also known as ‘dropless after cataract surgery’ (DACS) (n.b. this...

An unusual case of acute retinal necrosis

Case report A 40-year-old Caucasian male presented with a four-day history of redness and progressive painless reduction of vision in the left eye. His visual acuities were 6/4 in the right and 6/36 in the left. The left eye showed...

Severe conjunctival cicatrisation secondary to chronic glaucoma therapy

The timing of glaucoma filteration surgery during the course of chronic progressive glaucoma remains a contentious issue amongst glaucoma specialists. The vast majority support the use of maximal medical treatment initially to achieve the target pressure. Surgical procedures are only...

Pathophysiology of diabetic macular oedema: why combination therapy may be better

The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

What's trending Apr/May 2023

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Cyborgeye #flashlighteye #prostheticeye #BrianStanleyeye Brian Stanley is a California-based engineer, who lost his eye to retinoblastoma when he was six-years-old. A...

The results of the last survey Jun 2020

Firstly, my sincere thanks to those of you who responded to last edition’s survey. We had a record response. Laser was never my most exciting clinical treatment, but in this environment how I wish for even that degree of patient...

Intraocular surgery and dry eye: Understanding the link, minimising the risk and preparing for the future

Dry eye disease (DED) and ocular surface disease (OSD) are increasingly recognised as central factors in contemporary intraocular surgery. As cataract, glaucoma and vitreoretinal procedures advance toward greater refractive precision, patient expectations have risen and tolerance for postoperative visual fluctuation...

Oct/Nov 2018 Quiz

History A 37-year-old male was referred from the Emergency Eye Clinic with a swollen right upper eyelid. Symptom relieved with nonsteroidal anti-inflammatory drugs (NSAIDs). The initial clinical diagnosis was dacryoadenitis. The patient presented again six weeks later with 3mm proptosis,...

Cataract surgery in corneal disease

Cataract surgery in the presence of corneal disease presents multiple challenges, from determining whether symptoms are lenticular or corneal in origin, to decisions regarding timing of surgery, intraocular lens (IOL) power calculation, IOL selection, surgical technique and perioperative care. Realistic...