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Adjunctive topical 5-FU vs. MMC for surgically excised, localised OSSN

1 October 2014 | | EYE - Cornea, EYE - General | OSSN, chemotherapy, ocular oncology, ocular surface tumours
Ocular surface squamous neoplasia (OSSN) comprises a range of dysplasia including corneal-conjunctival intraepithelial neoplasia and invasive squamous cell carcinoma. The traditional treatment for localised non-invasive OSSN has been surgical excision with or without intraoperative cryotherapy. Postoperative adjunctive topical chemotherapy significantly...

Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)

1 April 2017 | | EYE - Pathology, EYE - Oncology | Atopia, Inflammation, Masquerade, Neoplasia, Ocular surface
The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...

Management of diffuse OSSN with topical chemotherapy

1 June 2015 | | EYE - Paediatrics, EYE - Strabismus
Ocular surface squamous neoplasia (OSSN) can be localised to the conjunctiva or, less commonly, diffusely spread over the conjunctiva and cornea. Localised OSSN can be treated by surgical removal with adjuvant cryotherapy and chemotherapy with low rates of recurrence. Diffuse...

Analysis of needle site after intravitreal injection for retinoblastoma

1 April 2017 | | EYE - Paediatrics, EYE - Strabismus
This study analysed the needle washings from retinoblastoma (RB) eyes receiving intravitreal Melphalon to consider risk of tumour externalisation from the procedure – 280 injections to 63 eyes in 61 patients were evaluated. Unilateral RB was present in 24 patients...
British Journal of Ophthalmology cover image.

Histopathology-guided management of ocular surface squamous neoplasia (OSSN) with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy

11 January 2024 | | EYE - Pathology, EYE - Oncology | conjunctiva, eye (globe), pathology, salivary gland
This is a retrospective interventional consecutive case series of 42 eyes of 42 patients with OSSN with histopathologically proven corneal stromal and / or scleral invasion following excision biopsy. The mean tumour basal diameter was 9.3mm and thickness of 3.1mm...

BSRS (British Society of Refractive Surgery) 30th Anniversary Annual Scientific Congress 2023

8 July 2023 -9 July 2023
by Hasan Naveed, YO Representative on BSRS Council. The summer weekend of 8-9 July 2023 saw the British Society for Refractive Surgery (BSRS) host national and international experts and colleagues passionate about all elements of refractive surgery. The sessions, delivered...

A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention

1 December 2015 | | EYE - Oculoplastic, EYE - Orbit
To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....

ARU opens Sensory Sciences Centre in Cambridge

1 February 2024 | university, infrastructure, Anglia Ruskin, clinic, education, trainees, courses, study, optometry, optometrist
New £1.9m investment in equipment, teaching and research space for students.

Eyecare entrepreneur is awarded an MBE

1 July 2024 | industry, awards, appointments, Body Doctor
Yorkshire businesswoman Sue Grant, the Co-Founder and Managing Director of The Body Doctor Ltd, has been awarded an MBE for Services to Entrepreneurship in the King’s Birthday Honours.

An anterior segment lump: a diagnostic and treatment challenge

2 February 2024 | | EYE - Oncology, EYE - Pathology
Case presentation A 50-year-old female presented to eye casualty with a lump on the left medial lower eyelid with associated redness and occasional bleeding. The lump was present for a few months with recent enlargement (Figure 1). Her past medical...

Move 78

1 August 2017 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
The Soviet Union still existed throughout my formative years, along with a vague undefinable miasma of possible war that generated films such as Red Dawn and Rocky IV. My favourite film from that era was called War Games, in which,...

Informed consent – the Brexit test

1 August 2016 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
The Medical Defence Union (MDU) runs courses on various medicolegal topics. I would guess people only ever attend these courses if they have an exam or an interview approaching as the subject matter is exceedingly dry for clinicians. I myself...