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Innovation update: key advances in eyecare transformation in the last year

Vishal Shah and his co-authors reflect on examples of innovation in eyecare delivery published in the last year and the implications for the future of eyecare services. The “new normal” is an overused phrase to describe extraordinary measures that have...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

Vitreomacular traction: natural course vs. vitrectomy vs. ocriplasmin

Over time, the vitreous gel completely separates from the retina in a process known as a posterior vitreous detachment (PVD). In some instances, however, the vitreous does not detach entirely and remains adherent to the macula. The term vitreomacular traction...

Is patient masking leading to an increase in post-op infection after eyelid surgery?

Due to the COVID-19 pandemic, the use of facemasks or face coverings in the clinical setting has become necessary. It is important to recognise that facemasks can be a source of infection after eye surgery and consider ways to minimise...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Q&A: Mr Goel and Mr Loomba on alcohol delamination and phototherapeutic keratectomy (PTK) for the treatment of recurrent corneal erosion syndrome

Recurrent corneal erosion syndrome is a common, recurrent condition caused by abnormal epithelial adhesion to the underlying basal lamina. Spontaneous breakdown of the corneal epithelium can lead to the sudden onset of ocular pain, blurred vision, tearing and photophobia, typically...

A window to 2024 and beyond?

The connection between the eye and systemic diseases has been acknowledged for millenia. Historical records suggest that ancient civilisations had some understanding of the eye’s significance beyond its primary function in vision. For instance, in ancient Egypt, the ‘Eye of...

My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Too bright to ignore: More than half of drivers affected by dazzling headlights say the problem is worse this winter than last

More than half of drivers who are dazzled by headlights – 57% – say the problem has worsened over the last 12 months with only three-in-10 (31) disagreeing, found comprehensive new RAC research supported by The College of Optometrists [1]....

The role of inflammation in the pathophysiology of DMO

Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Pathophysiology of diabetic macular oedema: why combination therapy may be better

The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

The use of toxin in paediatric strabismus

Strabismus is a common condition that affects up to 5% children and can be associated with abnormal visual development, double vision, loss of depth perception and impaired binocularity [1]. It can also cause cosmetic concerns, negatively impact psychosocial wellbeing and...