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A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
Surgical outcomes of isolated medial rectus palsy
Isolated medial rectus is a rare clinical entity. This prospective study of 32 patients from China showed that this was caused most commonly by iatrogenic injury (43.75%), trauma (37.50%) and congenital (18.75%) causes. An average of 60 ±25 prism dioptres...
Surgery to collapse V exo
This paper describes a case report of an extra-large V pattern measuring >60PD and the surgery required to collapse the pattern. The patient was a female aged 20 years. Angle measurements were 70PD at distance and 75PD at near in...
Therapeutic options for advanced cutaneous basal (BCC) and squamous cell carcinomas (SCC)
This article discusses the use of topical and systemic therapy in the management of advanced periocular tumours. It focuses on those that have gained United States Food and Drug Administration approval; namely imiquimod, vismodegib, sonidegib, pembrolizumab and cemiplimab. Imiquimod is...
Risk of pulled-in-two syndrome
Congenital fibrosis of the extraocular muscles (CFEOM) is along the risk factors for pulled-in-two syndrome (PITS). The aim of this study was to report six cases and discuss prevention and clinical management strategies. The author’s six cases represented an incidence...
Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations
Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...
Augmented surgery with BTA for large angle strabismus correction
This retrospective study reports the results of botulinum toxin A (BTA) augmented bilateral recession or monocular recession / resection (RR) for patients with large angle strabismus. Twenty-four patients were recruited: 10 female, mean age 9.2 ±13.6 years, 20 esotropia and...What's trending Aug/Sep 2021
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #algae #optogenetics Scientists in Paris have used optogenetics to partially restore sight in a blind man’s eye who was diagnosed with...SEEN by Joshua
They were all SEEN by one individual who then took their story to the world to witness. He saw them through his eyes and captured them in his camera lens. Through his vision and through their visual interpretations, an extraordinary,...Getting started in ophthalmology: Advice for new doctors
Starting your first rotation in ophthalmology is exciting and a little daunting. As the start date approaches, the nerves may start to creep in. What’s expected of me? How much ophthalmology am I supposed to know? How will the on-calls...
SS-OCT assessment of ITC after phacoemulsification
This is a multicentre randomised controlled trial of 22 patients with primary angle closure glaucoma with peripheral anterior synechia and peripheral primary angle closure glaucoma (PACG) with peripheral anterior synechia (PAS) detected by indentation gonioscopy was randomised into two groups....
