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2483 results found

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Early diagnosis of pituitary apoplexy using combined MRI findings

The author presents a literature review searching the terms ‘pituitary ring sign’ and ‘sphenoid sinus mucosal thickening’ in the context of pituitary apoplexy from 1990 until the present day. These two findings are both magnetic resonance imaging (MRI) signs of...

Managing orbital compartment syndrome

This experimental study using cadaveric models was done to evaluate the surgical technique effective in relieving orbital compartment syndrome. Twelve cadaveric orbits were injected with blood analogue stained with fluorescein. Pressure probes were inserted in superotemporal (advanced 40mm into orbit)...

IOP measures after intraocular chemotherapy

This study aimed to describe the relationship between intravitreal chemotherapy and IOP in children with retinoblastoma and identify risk factors for pronounced elevations. This was a retrospective study of ten cases (ten eyes) with 17 encounters overall. Mean age was...

Effectiveness and Safety of Dexamethasone implants for post surgical macular oedema including Irvine-gass syndrome

This is a retrospective, multicentre, uncontrolled, consecutive case series from Lyon, France between April 20111 to June 2014, with minimum of one year follow-up. The clinical features including the best corrected acuity (BCVA), central subfield macular thickness (CSMT) and intraocular...

Managing blepharophimosis

The authors present a prospective study of a one-stage technique for managing both telecanthus and ptosis seen in blepharophimosis syndrome. The technique involves carrying out a Y to V medial canthoplasty followed by a frontalis suspension which the authors carry...

Binocular summation with low contrast

The magnitude of binocular summation was investigated in normal control subjects using four different letter charts of varying type with fixed and variable contrast levels and spatial frequency to determine which tests most readily reveal binocular summation in normal subjects....

Optic nerve head perfusion response to reduced blood pressure and increased intraocular pressure

The purpose of this prospective study was to test the hypothesis that blood flow autoregulation in the optic nerve head has less reserve to maintain normal blood flow where there is a blood pressure induced decrease in ocular perfusion pressure...

Long-term retinal changes following unilateral retrobulbar optic neuritis

The aim of this study was to assess the longitudinal changes in retinal nerve fibre layer (RNFL) thickness after a first attack of optic neuritis and to investigate the impact of treatment on RNFL thinning at one year after the...

Atropine penalisation for amblyopia in the UK

The authors aimed to determine the current clinical practice of atropine penalisation (AP) in the UK, to identify perceived barriers limiting use of AP as a first line treatment and ascertain whether any of the barriers could be resolved. An...

Fixation disparity measurement

The authors evaluate different procedures looking at point zero, fixation disparity (FD) and motor fusion amplitude in order to calibrate the measurement of FD with Ogle’s apparatus with the overall goal to create a standardised measurement of the FD curve...

Orthoptic Cochrane reviews

The purpose of this study was to explore the Cochrane Eyes and Vision (CEV) library to extract and overview protocols and systematic reviews of relevance to orthoptic practice. A full database search was made of the 2016 library. Twenty-seven systematic...