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Current Eye Research journal cover image.

The effect of everolimus on retinal pigment epithelium and proliferative vitreo-retinopathy

1 August 2018 | | EYE - Vitreo-Retinal
The principal cells involved in proliferative vitreo-retinopathy (PVR) are retinal pigment epithelial cells (RPE). Everolimus is a drug used in renal cell carcinoma which targets and inhibits a key regulatory protein in cancer (mTOR). In this study, the authors investigated...
Current Eye Research journal cover image.

Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)

1 October 2018 | | EYE - Vitreo-Retinal
The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...
Ophthalmology Retina journal front cover image.

Infliximab in treatment of PVR

28 February 2025 | | EYE - Vitreo-Retinal
In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...
Seminars in Ophthalmology journal cover image

Intravitreal Ziv-Aflibercept: safety analysis

7 December 2020 | | EYE - Vitreo-Retinal
Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...
Journal of Pediatric Ophthalmology & Strabismus cover image.

Use of pattern-reversal VEP in congenital Zika syndrome (CZS) assessment

1 February 2022 | | EYE - Paediatrics, EYE - Strabismus
The authors conducted pattern reversal visual evoked potential (PRVEP) in children with congenital Zika syndrome (CZS) and report the correlates with visual acuity, fundus alterations and severity of microcephaly at birth. This was a cross-sectional study of 37 children with...
Ophthalmic Genetics cover picture

Choroideremia in women

2 June 2025 | | EYE - Vitreo-Retinal
The authors report a questionnaire-based study of female carriers of choroideremia, an X-linked inherited chorioretinal dystrophy. As an X-linked condition the full clinical features are predominantly seen in men but a proportion of women suffer some morbidity, likely due to...

Belfast briefing: Retina Day roundup from the RCOphth 2024 Annual Congress

2 August 2024 | | EYE - General
Belfast hosted this year’s Royal College of Ophthalmologists’ (RCOphth) Annual Congress, a meeting dedicated to sharing advances, knowledge and clinical practice points in ophthalmic care. This article summarises selected talks by medical and surgical retina specialists during the Retina Subspecialty...

Quiz Feb/Mar 2024

2 February 2024 | | EYE - Oncology, EYE - Pathology, EYE - Paediatrics, EYE - Strabismus, EYE - General
History A 21-month-old boy presented to his local ophthalmology department with a left proptotic eye from a growing cystic lesion known to be present from birth. Notes taken on presentation were: Known left microphthalmia with chorio-retinal coloboma, contralateral eye was...

Leveraging networks and collaboration: The Calabar Diabetic Retinopathy Service, from inception to a state-wide service, research and training hub

3 June 2026 | | EYE - Vitreo-Retinal, EYE - Imaging
Diabetic retinopathy (DR), a microvascular complication of diabetes mellitus (DM), is a leading cause of preventable vision loss and blindness in people of working age globally [1]. Diabetic retinopathy is a disease of public health importance in Nigeria as it...

Phaco nightmares

1 October 2018 | | EYE - Cataract, EYE - Refractive, EYE - General
I am interested in the stressful nature of cataract surgery from the surgeon rather than the patient’s perspective. It is an issue that has quite literally kept me awake at night. Part of getting to grips with a problem is...

Do we really need the College to be Royal?

6 April 2021 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
It is taken for granted in this country that all the best medical colleges are Royal. That they have the royal seal of approval from on high and therefore must be the best. I have been somewhat confused for a...

A case of late spontaneous subluxation of in-the-bag intraocular implant

1 April 2017 | | EYE - Cataract, EYE - Refractive
An 82-year-old frail lady was referred by her optometrist with a finding of subluxated implant in the right eye. She had uneventful phacoemulcification with in-the-bag intraocular implant 17 years earlier. There is no history of having had pseudoexfoliation (PXF) or...