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Reduced blood flow and age-related macular degeneration
1 August 2014
| Khadijah Basheer
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EYE - Vitreo-Retinal
This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...
Effects of blood donation on the physiology of the eye
1 December 2018
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...
OCT-A imaging in Grave’s orbitopathy and orbital decompression
In this case series of 12 patients and 24 orbits, the authors describe the changes in the optic nerve and peripapillary blood vessel density in patients with moderate to severe Grave’s Orbitopathy (GO) undergoing orbital decompression. The patients undergoing orbital...Intraocular pressure changes following TOHM washout
1 December 2021
| Jonathan Chan
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EYE - Glaucoma
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IOP phasing, prospective clinical trials, uveitic glaucoma
This retrospective study between 2008 and 2019 of 110 eyes with primary open angle glaucoma (POAG), 33 eyes with ocular hypertension (OHT) and 43 eyes with uveitic glaucoma (UG) evaluated the changes in intraocular pressure (IOP) following topical ocular hypotensive...
Differences between ages and onset in functional network changes associated with reading Braille
1 December 2021
| Claire Howard
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EYE - Neuro-ophthalmology
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Braille, early blind, fMRI, functional connectivity, late blind, voxel-based morphometry
Visual impairment affects learning ability, speed and accuracy required for reading, writing and learning memory in terms of educational performance. Braille training requires decoding of simple dots into meaningful words and sentences. The objectives of this study were to evaluate...
Screening for visual processing deficits in dementia
5 April 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Dementia, cognitive impairment, screening test, visual deficits, visuospatial
The Queen Square Screening test for Visual Deficits (QS test) screens for changes in visual processing. It has never been formally validated as a single test. The test consists of a short booklet developed using remnant object and spatial perception...
Using optical coherence tomography angiography to detect MoyaMoya vasculopathy
5 April 2022
| Claire Howard
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EYE - Neuro-ophthalmology
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Neuro-ophthalmology, moyamoya vasculopathy, optical coherence tomography angiography, retina
Moyamoya (MM) disease is a chronic cerebrovascular disease that can lead to progressive stenosis of the terminal portions of the internal carotid arteries and their proximal branches. The authors carried out a cross-sectional cohort study to investigate vascular changes in...
Pilot trial of virtual reality to treat amblyopia beyond the age of seven years
A pilot double-blind randomised controlled trial is presented. Patients were required to be between seven and 38 years of age, have a diagnosis of anisometropic and / or strabismus unilateral amblyopia, visual acuity in the amblyopic eye between 0.3-1.0 LogMAR...Foveal displacement after macular hole surgery
5 April 2022
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Foveal displacement, internal limiting membrane peeling, metamorphopsia, papillofoveal distance, temporal inverted internal limiting membrane flap
Previous studies show that internal limiting membrane (ILM) peeling during macular hole surgery is associated with retinal shrinkage (microtubule depolymerization of the axons of the inner retina) and nasal shift of the fovea. A temporal inverted ILM flap technique was...