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3223 results found

Aquaporin-4 antibody testing in isolate optic neuritis

The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...

Transsynaptic retrograde degeneration linked to homonymous visual field loss after stroke

centre, of individuals identified with homonymous visual field loss post ischaemic stroke. Exclusion criteria were bilateral ischaemia, anterior / pregeniculate visual pathway affected and other pathology with the potential to effect visual fields. The following were extracted from the medical...

Case presentation: seizures as a presenting sign of idiopathic intracranial hypertension

Idiopathic intracranial hypertension (IIH) is a syndrome of isolated elevated intracranial pressure of unknown cause. Neurological examination in IIH is typically normal except for papilloedema and possible cranial nerve six palsy, although rare, atypical symptoms and signs can occur. With...

Characteristics of neuro-ophthalmic visual disturbances post-cataract surgery

The authors present a retrospective case review of adult patients seen by neuro-ophthalmology over a nine-year period. The aim of the study was to identify the cause of neuro-ophthalmic referrals within six months of cataract surgery. Individuals already known to...

PAX6 methylation and myopia

The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...

Covid-19 ophthalmopathy

Ocular involvement is not uncommon in patients with Covid-19. However, the incidence of Covid-19 ophthalmopathy is unclear. The authors present a prospective case series including 2445 consecutive cases presenting at a neuro-ophthalmology clinic during the last resurgence of SARS-CoV-2 infection....

Characteristics of central serous chorioretinopathy by age

The authors present a cohort study of 326 patients with simple central serous chorioretinopathy (CSC) according to the classification system laid down by Chhablani, et al. in 2020. Genotyping for two variants of the CFH gene rs800292 and rs1329428 was...

Tocilizumab effectiveness in paediatric non-infectious uveitis: data from the International AIDA Network Registries on ocular inflammatory disorders

Medical records of 15 paediatric patients (onset before age of 16) affected by refractory non-infectious uveitis (NIU) and treated by tocilizumab (TCZ) were reviewed. Data were extracted from the international AIDA Network for uveitis registry and Behcet’s disease registries. They...

N-T asymmetry in tracking eye movements

The current study aimed to quantify and compare the visual tracking responses of two sensory induced strabismic juvenile monkeys during monocular smooth pursuit, ocular following response and optokinetic nystagmus (OKN). Monkey 1 had esotropia and monkey 2 had exotropia. Both...

Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)

The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...

Effect of heredity on risk of diabetic retinopathy

This study used survival analysis on 2199 patients who had reached vision-threatening diabetic retinopathy to investigate the contribution of heredity to diabetes together with other known risk factors for the development of either proliferative diabetic retinopathy (PDR) or diabetic macular...

Comprehensive review of inherited retinal diseases

The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...