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Late stromal rejection in DALK
This case series reported on late stromal rejections in eyes after uncomplicated deep anterior lamellar keratoplasties (DALKs). Four eyes of three patients experienced episodes of isolated stromal rejection 33 to 46 months after surgically uncomplicated DALKs and a minimum of...
Allergic eyelid dermatitis
This is a retrospective 12 year review of 61 patients diagnosed with periocular allergic dermatitis. The average age was 66 years, with 74% being female. The commonest indications for referral were epiphora, ectropion and blepharitis; and the main symptoms were...Feb/Mar 2016 Quiz 2
History A 30-year-old male presents with a phthisical left eye and undergoes enucleation. He has some lesions in his right eye that are under ophthalmic surveillance. Figure 1 is a low power of the enucleation. Figures 2, 3 and 4...Jun/Jul 2018 Quiz
History A 35-year-old woman had a long-standing left blind eye following extensive exudative retinal detachment in the past. She later developed increasing pain in her blind eye. Her medical history includes pheochromocytoma resected five years ago, and she is currently...
Long-term outcomes for hereditary retinoblastoma
Earlier diagnosis and more rigorous treatment regimens have contributed to better outcomes for patients with retinoblastoma. This study looked at 24 patients with hereditary bilateral retinoblastoma treated with systemic chemotherapy during a ten year period (2001-2011). The medical notes were...
Episcleral brachytherapy (EB) for retinoblastoma (RB)
This retrospective study consisted of 11 eyes treated either with Iodine (I) -125 or Ruthenium (R) -106EB with a mean apical dose of 44Gy. There were five in group B (46%), three in group C (27%) and three in group...
A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
Review of paediatric open globe injuries in the US
This study used the Nationwide Inpatient Sample (NIS) database to describe the trends in types, demographics and incidence of paediatric open globe injuries in the US. The NIS database covers about 97% of the US population and about 20% of...
Presenting and diagnostic signs of retinoblastoma
This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...
Proof of concept for using aqueous humour to detect retinoblastoma variant
A proof of concept study is presented with the aim of assessing the feasibility of using aqueous humour surrogate marker for tumour tissue for identifying retinoblastoma RB1 variant. Three children undergoing enucleation for retinoblastoma were recruited from a single centre....
Management options for microphthalmia with orbital cyst with / without visual potential
The authors present six cases (seven eyes) of congenital microphthalmia and orbital cyst. These cases were newborn mainly with one aged 20 years. There were four females and two males and two of seven eyes had a visual potential of...
