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Driving with the use of spectacle mounted telescopes (bioptics)

The authors discuss the current perspectives of spectacle mounted telescopes (bioptics) whilst driving among patients with visual impairment. The history, design and driving laws surrounding the use of bioptics is discussed in detail. In 1977, William Feinbloom developed a bioptic...

Who will benefit from cataract surgery?

The need for cataract surgery is expected to rise dramatically in the future due to the increasing proportion of elderly citizens and increasing demands for optimum visual function. The aim of this study was to provide an evidence-based recommendation for...

Using OCT to screen and monitor Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...

Somatostatin protects retinal pericytes

Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...

Same day air bubble removal after DSEK/DSAEK

A complete air removal on same day as descemet’s stripping endothelial keratoplasty (DSEK/DSAEK) leads to prompt restoration of the anterior chamber and thus has been hypothesised to assist with the recovery of endothelial function and promote graft adhesion. The results...

Postop improved fusion and stereopsis in IDEX

This study aimed to evaluate changes in binocular visual function in patients with different ages before and after surgery to explore the optimal timing of intermittent exotropia surgery. The study comprised 28 females and 25 males. Fifty-three patients were split...

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Do operative interventions for IIH improve visual function?

The authors of this paper reviewed patient case notes to determine visual outcome following shunt surgery for idiopathic intracranial hypertension (IIH). A retrospective case notes review was conducted for 50 patients who underwent shunt surgery for IIH. Outcome measures included...

A diagnostic imaging technique for optic pathway tumours

The authors discuss the difficult clinical scenario of patients with deteriorating visual function and an optic pathway lesion. The morbidity associated with biopsy means a highly sensitive and specific imaging technique would be of great value. The authors describe the...

Results of surgery in a case of FMNS

The authors present the effects of the tenotomy and reattachment procedure on a patient with accommodative strabismus and fusion maldevelopment nystagmus syndrome (FMNS) who did not require strabismus correction. The ocular motility study of this patient allowed the opportunity to...

Effect of phacoemulsification on trabeculectomy function

Previous studies have reported cataract surgery post trabeculectomy to be detrimental to IOP control. Conversely, other studies have reported phacoemulsification performed before trabeculectomy as a factor for bleb failure. The objective of this retrospective case control study was to evaluate...

Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide

X-linked retinoschisis (XLRS) is an early onset hereditary retinal dystrophy. It is caused by mutations of the RS1 gene. Common manifestations of XLRS are schitic lesions at the macula, as well as infero-temporal schisis. Carbonic anhydrase inhibitors have previously been...