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Retinal changes prior to hydroxychloroquine toxicity
In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...
Effect of long-term RGP-CL wear on keratoconus progression
This is a retrospective study between April and December 2017, of 22 rigid gas-permeable contact lens (RGP-CL) patients (31 eyes) and 15 non-CL patients (20 eyes) who fulfilled the criteria of: 1) >3 years follow-up and 2) Scheimpflug-based corneal imaging...
Intraocular pressure changes following TOHM washout
This retrospective study between 2008 and 2019 of 110 eyes with primary open angle glaucoma (POAG), 33 eyes with ocular hypertension (OHT) and 43 eyes with uveitic glaucoma (UG) evaluated the changes in intraocular pressure (IOP) following topical ocular hypotensive...
Using lumbar puncture as a diagnostic tool of IIH when the presentation is typical
The authors present the findings of a retrospective observational chart review across three neuro-ophthalmology clinics. Databases at each clinic were searched using inclusion criteria based on established diagnostic criteria for idiopathic intracranial hypertension (IIH). Cases with missing data, atypical findings...
Lagophthalmos as a potential complication of COVID-19
Lagophthalmos is a condition associated with the inability to close the eyelids effectively, with the main cause being facial nerve palsy. The authors aimed to investigate whether lagophthalmos was associated with coronavirus infection (COVID-19) by comparing patients diagnosed with lagophthalmos...
Central fixation testing in microtropia
This study compared the two assessment methods of the 4D prism test and ocular fixation assessment in order to identify micro strabismus with identity. The study included 112 children; 46 males and 66 females. Anisometropia was present in 108 patients...
Presenting and diagnostic signs of retinoblastoma
This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...
Aflibercept (AF) for age-related macular degeneration (ARMD): four-year outcomes of a ‘’treat-and-extend’ (T&E) regimen with exit-strategy
This is a retrospective observational study of 82 patients, between 2014 to 2016 from Switzerland of treatment-naive patients with nARMD, treated with AF, with specific T&E protocol without a loading phase and predefined exit criteria and patients were observed three...
Outcomes of combined medial and laser treatment for advanced Coat’s disease
In this study, the anatomical and visual outcomes of paediatric patients with advanced stage 3+ Coat’s disease are reported. Patients were treated with a combination of intravitreal ranibizumab, laser photocoagulation and methyl prednisolone acetate. This was a retrospective review of...
Saccadic measurements in intermittent exotropia vs fusional amplitude
The authors investigated the correlation between fusional convergence amplitude and saccades during the shift from exotropia to binocular fixation during the cover / uncover test. This was an observational study of 15 patients (six female, nine male) with intermittent exotropia....
Two-year results of a T&E aflibercept regime in caucasian PNV
This a retrospective study examining two-year outcomes of patients with pachychoroid neovasculopathy (PNV) treated with a treat and extend (T&E) regimen of intravitreal aflibercept. The mean age was 63.84 ± 7.92 years with nine males (35%) and 17 females (65%)....
