You searched for "impaired"
Combined anti-VEGF and PDT for wet AMD
The authors report on a retrospective case series of combined anti-VEGF and photodynamic therapy (PDT) in the treatment of wet age-related macular degeneration (AMD) refractory to anti-VEGF monotherapy alone. The criteria for treatment failure of anti-VEGF monotherapy were persistent subretinal...
Four year outcomes of macular degeneration treated with ranibizumab
The authors report on a retrospective study of neovascular age-related macular degeneration (AMD) patients treated with a variable ranibizumab dosing regimen over a period of four years (from January 2007 to December 2011). A total of 600 treatment naïve eyes...
Cataract surgery in patients with Vogt-Koyanagi-Harada
This retrospective, interventional case series of 286 patients (408 eyes) assessed visual outcome and prognostic factors in patients with Vogt-Koyanagi-Harada (VKH) undergoing cataract surgery between September 2008 and December 2017. Two groups were reviewed. The first group (352 eyes) had...
Combined PRK and CXL in keratoconus
This study aimed to investigate the results after photorefractive keratectomy (PRK) followed immediately by standard 30-minute corneal cross-linking (CXL) for keratoconus. This retrospective study included 26 eyes of 16 patients with keratoconus. Uncorrected distance visual acuity (UDVA), corrected distance visual...
Improving reading of fundus photographs in an emergency setting
The first phases of the FOTO-ED study found that emergency providers perform significantly better with fundus photography than with direct ophthalmoscopy in the detection of fundus abnormalities. The authors hypothesised that by providing additional training to emergency providers, this would...
Subthreshold micropulse laser in BRVO
The purpose of this retrospective, consecutive, single-centre, non-randomised, and case-control study was to verify the therapeutic effects and safety of oedema (from branch retinal vein occlusion (BRVO)) recurrence suppression effect using 577-nm subthreshold micropulse laser photocoagulation (SMLP) in combination with...
Injection of methotrexate into silicone oil-filled eyes for grade C PVR
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
Near-infrared autofluorescence to diagnose retinal laser injuries
This retrospective observational case series aimed to assess whether near infrared autofluorescence (NIR-AR) imaging is a useful imaging modality in the diagnosis of hand-held laser retinal injuries. Twelve patients from two centres underwent ophthalmic assessment and retinal imaging including fundus...
RPE tears in cases of IPCV
The aim of this study was to investigate the occurrence, characteristics, management and prognosis of retinal pigment epithelium (RPE) tears in patients with polypoidal choroidal vasculopathy (PCV). Medical records of previous cases were reviewed over an eight-year period from a...
Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD
This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...
Silicone oil migration presenting as an eyelid cyst
The author presents a single case report of a rare complication of silicone oil tamponade, silicone oil migration, after pars plana vitrectomy. A seven-year-old female, with a history of vitrectomy one year prior for penetrating eye trauma, presented with a...
