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Complement factor B polymorphism and the phenotype of early age-related macular degeneration
1 August 2014
| Huw Edward Oliphant
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EYE - Vitreo-Retinal
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
The prevalence of macular cysts in patients with clinical cone-rod dystrophy determined by spectral domain optical coherence tomography
1 August 2014
| Huw Edward Oliphant
|
EYE - Vitreo-Retinal
Cone-rod dystrophy is a progressive photoreceptor disorder which has multiple inheritance patterns. It is rare, with a prevalence of 1 in 40,000. Macular cysts are well recognised in other photoreceptor conditions such as retinitis pigments and choroideraemia, while they are...
Liquid adhesive bandage for clear corneal cataract incisions
This paper reports a prospective randomised controlled trial of patients undergoing routine phacoemulsification with a 2.75mm clear corneal incision and followed up for 14 days postoperatively. They evaluated wound edge closure, surgically induced astigmatism and foreign body sensation after use...A relationship between central serous retinopathy and obstructive sleep apnoea
This prospective study aimed to evaluate a relationship between central serous retinopathy (CSR) and obstructive sleep apnoea (OSA). Twenty-three subjects (six female and 17 male) were diagnosed with CSR and overnight polysonography was performed to record desaturation and apnoeic episodes....Case reports of neuro-ophthalmological complications of CIPD
1 April 2014
| Claire Howard
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EYE - Neuro-ophthalmology
The authors present three cases of neuro-ophthalmological complications of chronic inflammatory demyelinating polyradiculoneuropathy (CIPD). CIPD can lead to prominent nerve hypertrophy which can mimic other forms of neuropathy radiologically. In addition, complications can occur which can cause diagnostic difficulties. All...
Prognosticating ocular adnexal lymphoma
1 April 2014
| Konal Saha
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EYE - Orbit
The authors retrospectively analyse 160 patients with primary ocular adnexal lymphoma to determine the accuracy of prognosis based on the Ann Arbor classification and how this compares to the accuracy of prognosis based on retrospectively applying the newer Tumor, Node,...
The impact of collagen crosslinking on keratoplasty numbers in keratoconics
A question of corneal cross-linking (CXL) reducing keratoplasty numbers in keratoconics was addressed in this single centre observational study from the Oslo University Hospital – a sole provider of keratoplasties and CXL for a population of 2.8 million. Authors compared...Selection of visual field test for detection of pituitary disease
This prospective cross-sectional diagnostic accuracy study compared Octopus semi-automated kinetic perimetry (SKP) and Humphrey static automated central perimetry for detection of neurological visual field loss in patients with pituitary disease. Humphrey central 30-2 SITA threshold programme results were compared with...Smoking and Behçet’s disease
1 October 2015
| Saruban Pasu
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EYE - Vitreo-Retinal
This study aimed to investigate the relationship between smoking and prognosis of ocular Behçet’s disease (BD). Records of 202 patients with ocular features of BD were reviewed from a Turkish hospital. Patients were divided into two groups according to their...
Chronic drop use and trabeculectomy on tear osmolarity
1 February 2014
| John Brookes
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EYE - Glaucoma
Ocular surface disease (OSD) is common in patients chronically treated for glaucoma. This may be related to the drug itself but often to the preservatives in the medication. Much work has been done on the most common preservative, benzalkonium chloride...
Modern trabeculectomy outcomes
1 February 2014
| Brian Ang
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EYE - Glaucoma
This audit was conducted by the Trabeculectomy Outcomes Group Audit Study Group to report on the efficacy and safety of current trabeculectomy surgery in the UK. This is relevant in light of the fact that the trabeculectomy outcomes presented by...