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Patients blinded by stem cells! How safe are they really?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Patients blinded by stem cells! How safe are they really? Ever since the successful results following...

Effect of voriconazole of vision of healthy volunteers

Voriconazole is a broad spectrum, triazole antifungal agent used for systemic fungal infections. It has a favourable safety profile and is available in both intravenous and oral forms. The commonest adverse drug reactions with voriconazole are changes in visual perception,...

Normal reference values for the RETeval device

The purpose of this study was to provide normative data of full-field electroretinography (ERG) responses in the paediatric population using the RETeval device in healthy children with normal retinas. This was a prospective study of 38 eyes of 20 patients...

Post-Brexit deal welcomed but leaves future relationship with EU far from settled

Rod McNeil breaks down the impact of the Brexit deal on healthcare in the UK, including medicines regulation, research funding, sharing of information and the ability to work abroad. A disorderly no-deal exit from the European Union (EU) was averted...

Allergic conjunctivitis evaluation by thermography

Thermography is a non-invasive imaging technique, which uses infrared radiation reflected from an object to estimate the temperature of the object. This paper evaluates the use of thermography to assess allergic conjunctivitis objectively, by using an instrument called ocular surface...

Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...

Grading of ocular inflammation in uveitis: an overview

Anterior uveitis is the commonest form of uveitis, which can lead to severe morbidity if not treated appropriately [1]. Data from general ophthalmology practices suggest around 90% of uveitis encountered by comprehensive ophthalmologists is anterior uveitis [2]. Intermediate (vitreous), posterior...

Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice

The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...

MR- vs. LR+ for divergence insufficiency

A retrospective study was conducted to compare the efficacy of medial rectus recession and lateral rectus resection as surgical interventions for divergence insufficiency in 18 patients. These were cases of non-neurological cause. Two patients in each group required postoperative adjustment....

Infantile exotropia and developmental delay

This is a retrospective review of infants requiring surgery for infantile exotropia before the age of one year to report the surgical outcomes and frequency of associated developmental problems. The study reviewed 26 patients first assessed at two to 10...

Outcomes of strabismus surgery for TED

This study investigated the surgical outcome according to the initial postoperative angle of deviation after strabismus surgery in patients with hypotropia and esotropia who had thyroid eye disease (TED). The study included 78 patients with mean age of 53.4 ±9.5...