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Limbal melanocytes and the stem cell niche

The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...

Lower postoperative scar height is associated with increased postoperative trichiasis one year after bilamellar tarsal rotation surgery

Bilamellar tarsal rotation has been a key component of the WHO SAFE approach to blindness from trichiaisis (surgery, antibiotics, facial hygiene, environment). The World Health Organisation (WHO) manual describes the procedure as a full thickness blepharotomy placed 3.0mm above and...

Combined Vismodegib and Mohs surgery

This is a report of eight patients with locally advanced periocular basal cell carcinoma who were treated with Vismodegib prior to Mohs micrographic surgery. The rationale for the combined treatment plan was that long-term Vismodegib is poorly tolerated due to...

OSCAR for anterior approach ptosis surgery

The authors report an International Council of Ophthalmology (ICO) Ophthalmology Surgical Competency Assessment Rubric (OSCAR) for anterior approach ptosis surgery. An international panel of content experts, representing Australia, India, Iran, Italy, Turkey, United Kingdom and the United States of America...

Ocular adnexal marginal zone b-cell lymphoma

This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...

Hidden spread of sebaceous cell carcinoma

This was a review of 29 patients who had undergone orbital exenteration for sebaceous cell carcinoma. Prompted by the increasing use of topical treatments for intraepithelial disease, the authors were keen to discover the frequency of spread of tumour cells...

Hydrogel expanders in the management of congenital anophthalmia

This is a retrospective case series of 11 anophthalmic orbits in eight children. Anophthalmia can result micro-orbitism, congenital fornix atresia, constricted socket, phimotic lids and reduced palpebral aperture. Expanders play an important role in improving the orbital volume and forniceal...

No risk of dry eye disease in concomitant strabismus cases

This preliminary assessment of the ocular surface of patients with concomitant strabismus before surgery was undertaken to determine if the presence of strabismus increases the risk of dry eye disease. This was a cross-sectional study of 204 patients with concomitant...

On the wrong track

A 65-year-old very high myope lady presented with sudden blurred vision down to count fingers to her right eye after a short and sharp pain. She also described seeing a black swirly line and as all these symptoms were exactly...

A closer look at the new wave of glaucoma surgery – radical or old school?

Glaucoma is a challenging condition to treat because the exact pathophysiology remains unclear and the only readily modifiable factor is the intraocular pressure (IOP). Additionally, most glaucoma patients are completely asymptomatic, yet are often subjected to lifelong medical therapy. The...

Effective management of dry eye and ocular surface disease

Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

The science of glaucoma management: highlights of the 2020 Moorfields International Glaucoma Symposium

Held earlier this year, the 12th annual Moorfields International Glaucoma Symposium provided a forum for advanced clinical and scientific exchange in glaucoma management. The authors describe the key presentation themes and debates, highlighting specific topics of interest to glaucoma specialists....